Could you elaborate this please?
He has to be like the best doctor ever
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I cann’t explain it since I do not know gene science either, it is super complicated which looks like this:
They said it is normal gene mutation happened because of the environment, they just want to find if some mutations are likely induced by finasteride exposure and may be responsible for my symptoms.
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Thank you very much, man.
You are welcome, take care.
Please, keep us updated. And good luck!
I was thinking about doing a full genome sequence of myself to.
If I did, do you think it would be able to cross reference our genomes and see if there is any overlap?
I am willing to share my result, but remember if you are going to do a entire human genes sequencing, you need a professional team analyze it for you, or it won’t make any sense.
Keep us updated about your doctor’s updates, he is doing realling great job!
What would be the cost of that?
my doctor and his team applied a program which is supported by a national medical research foundation, so the whole process cost me 0.
of course I will.
So your doctor is putting you top-grade HRT, analyzing your genome with a team of researchers, even going on fin himself to better understand the experience? And not charging you a cent! Holy shit, I could never imagine ANY western doctor going to this length to not just help you but try to find the root cause. This honestly seems like the type of study that would takes years and years to even get approved in the USA.
Huge fucking props to your doctor and his team, and honestly to China as well.
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I need pay for HRT and other medical cost, only the research won’t cost me a cent.
So far this doctor has only done @ Hanru_Sun’s full human genome sequence. You can wait for this doctor to do the full human genome sequence of other Chinese PFS patients and see if the same mutation exists.This will save you time.Anyway, we’ll share any new findings on the forum.
Hi all, some updates:
I met my doctor and the research team on 6.22, and we had a discussion. first of all, the research team promised to me that they checked my gene about AR at the first time they get my result, haven’t find any abnormal mutation, so the classical AR dis-function theory in this forum at least do not suit my case. They do found that the there are plenty of gene mutations which related to anxiety and depression, which may indicate hormone manipulation are much more likely to induce severe bad reaction on me. and they said they will further investigate more gene mutations about sexual aspect on me, it will take few more weeks.
After the discussion I go on for my road trip, today I get back to Beijing and finished a testicle ultrasound, which confirm my testicle size are still 13 ml and 14 ml, in normal range but small, no noticeable difference with 2 months ago, but 3 months ago (my worst time) they are only 11 ml, I lose about one third of my testicle size and it seems really stable now, even I am still on clomid. I also finished a blood test, not only about sex hormone but also include catecholamine (DA,E,NE) , IGF-1 and growth hormone, I will get the result in few days and after that, I will meet my doctor again.
For my current situation, I am going through some fluctuation, I get good news and bad news: For good news, I started taking proviron about 3 weeks ago, after 2 weeks, I noticed some difference: 1. I feel my libido increase from 0 to 20% pre-fin, right now sex thought make sense to me sometimes (majorly in the morning, like some spark). 2. Oragsm pleasure improved significantly, when I am watching a porn and masturbating, I can feel exciting again, before that for several months I just feel so blunted. 3. semen volume increased significantly, this already improved after hrt but almost pre-fin right now.
Bad news: 1.digestion system are not working well recently. 2. slight muscle twitching after intensive exercise, majorly on legs and hands, not as terrible as my crash, but still really annoyed. 3. still ED, I can get a full erection through porn and stimulation (take longer efforts than before and harder to maintain), but cann’t get it up when lying with a women, so I still not dare to try to have sex. 4. Nocturnal erection is still here, but morning wood is getting rare and rare. 5. anxiety is getting more severe and sometimes unbearable.
At last, I just finished a road trip and wish to share some beautiful scenery with you guys, this world is beautiful and of course worth living.
I will keep update about the further progress, this is a long battle and need patience, I am trying my best to keep mentally strong, pray for me and pray for you all.
Hanru.
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Beautiful photos!
I don’t think a mutation is what the commonly held belief is for an explanation of our condition.
Rather a modification in the epigenome via methylation. The genome itself is unlikely to be affected.
Thanks! I really do not understand gene science, what I can do is just waiting for their research, there will be more Chinese PFS patients gonna participate in this research in the future I believe, I hope they can find some thing meaningful.
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Beautiful photographs! I love seeing the landscape in different parts of the world. In what region were they taken?
Man you got the best doctor ever, I hope you realize how lucky you are compared to some of us.
We literally get told we are either lying or delusional.
Anyway, wonderful pics and good to know you’re managing your situation.
I just have one question for you: you are quite early into this mess, but nevertheless already taking hormones and hormones-altering drugs. Obviously you must have your reasons for this, but if you’re still in your first year/18 months of PFS you have a chance of improving on your own, how come you decided to opt for treatment?