6 years off the drug. Here my blood tests

[MeStupid]

Total Testosterone: 3.82 (2.8-9.0)
Free Testosterone: 7.7* (12-40)
Androstenedione: 4.0* (0.8-2.8)
Estradiol: 26 (15-45)
FSH: 3.64 (1-14)
SHBG: 31.7 (11-80)
Prolactin: 7.9 (3.0-15.0)
TSH: 2.73 (0.1-4.5)
DHEA: 239.0 (120-500)
PSA: 1.0 (0.0-4.0)

Cholesterol:
Total: 190 (120-200)
HDL: 59.2* (34-59)
LDL: 117.7 (40-130)

I have no ED or sexual problems (maybe less libido), but the real problem is that I have a cronic prostatitis (6 years). My stream is very weack and I have too pee very often.
Here my story: viewtopic.php?f=3&t=3949

In these years I’ve tried all the imaginable… from naturopathy, omeopathy, acupuncture, drastc diets, benzodiazepines… all useless… I have tryed many prostate oriented therapies… useless…

Can the “Free Testosterone: 7.7* (12-40)” and the “Androstenedione: 4.0* (0.8-2.8)” cause the problem?
Is there any therapy to try?

Any suggestion is welcome.

[Mew]

Free Testosterone: 7.7* (12-40)

Since Free T is what is biologically available to the body, an out of range low level seems like a source of potential issues.

Elevated Androstenedione points to a potential adrenal issue or issues with enzymatic/androgen metabolism pathways such as 17B-HSD, 5AR or 5B reductase.

Diagrams: viewtopic.php?f=4&t=518

What did your doc say about results?

[kazman]

I have elevated androstanedione as well as low free testosterone, and have the exact same urinary issues (along with the majority of symptoms on the list). My free T has been low starting with the first test 7 months after quiting fin, and is still frequently low even now 87 years later.

I can report that under the action of clomiphene (~ 25 mg 3 times a week) to raise total serum T my stream gets stronger and frequency of urge to urinate goes down.

What I think is happening is that we are suffering from hypoplasia (not hyperplasia) of the prostate. Finasteride was originally invented to treat an enlarged prostate - but in our case we suppress the 5 alpha reductase type 2 isoenzyme far more completely, and permanently, then expected. This causes our prostates to shrink to a smaller than normal size (a urologist once commented to me that my prostate was quite small) which leads to the frequent urge to urinate small amounts, and reduced ejaculate volume etc. kazman

[MeStupid]

@Mew

What did your doc say about results?

I have an appointment next week with my family doctor.
Things are very complicated, I think that I have to go to an endocrinolgist or an andrologist. Which one do you think is better for our problems?
I’ve seen on the diagram that cholesterol is involved. I’ll put also these values. (I have elevated “Good” Cholesterol - HDL).

@kazman

I can report that under the action of clomiphene (~ 25 mg 3 times a week) to raise total serum T my stream gets stronger and frequency of urge to urinate goes down.

How long did you stay on therapy? When you quit with clomiphene improvements go away?

@kazman

What I think is happening is that we are suffering from hypoplasia (not hyperplasia) of the prostate. Finasteride was originally invented to treat an enlarged prostate - but in our case we suppress the 5 alpha reductase type 2 isoenzyme far more completely, and permanently, then expected. This causes our prostates to shrink to a smaller than normal size (a urologist once commented to me that my prostate was quite small) which leads to the frequent urge to urinate small amounts, and reduced ejaculate volume etc. kazman

The urologists said me that i have a little bigger prostate than normal (and inflamed).

Thanks for your support.

[MeStupid]

First post updated with cholesterol values.

[kazman]

@kazman

I can report that under the action of clomiphene (~ 25 mg 3 times a week) to raise total serum T my stream gets stronger and frequency of urge to urinate goes down.

How long did you stay on therapy? When you quit with clomiphene improvements go away?

Each time I have “come off testosterone”, whether its topical testosterone, clomiphene citrate (3 times for various reasons, including to get a “clean” adiol-G value) and hCG, my urinary frequency and nighttime trips to the bathroom increased.