5htp - a treatment for brain fog?

Therapeutic Efforts Supplements & Lifestyle
#21

Yes ejcaulation volume and erections were improved as well but only for the time I took it. Once I got off the sexual improvements went away but the brain fog improvement stayed with me.

Overall I have a life sexually so I guess I should be grateful. I had no libido or erections the first 2 years off. The only thing that seemed to help was some korean ginseng. It improved after about 4 or 5 years to the point I am at now.

I have peyronies but no curve, I had some loss in girth and lenght.
ejaculation volume is much less than it used to be.
Morning erections are very rare.
I can have sex it just requires some stimulation. Wife is fine with that. IT took about 3 weeks to see improvement in the sexual sides as well.

#22

I have been taking 5 htp for 4 days now and have seen nothing at all. Is this consistent with your experience?

#23

Yes I didnā€™t notice anything for at least 3 weeks. How bad is your brain fog Tim and is it relieved by diet?

#24

I have first equal worst brainfog here. If i fast it clears a little.

#25

What dosage are you using? What brand?

#26

one week in i still havenā€™t seen much of a changeā€¦ though i do think i might be slightly less depressed and have a slight boost in energy. tim1911ā€¦ any changes? still using the stuff?

im at least gonna keep going for a month.

#27

Yes im still using and no change aswell. I am going to use for a month also. I hope it does something.

#28

Where can i get that?
How many people tried it and got erection back.?

#29

I did a search in google and people say it decrease libido.

#30

When I titled this post it was a bit misleading I donā€™t think itā€™s a cure for sexual issues but more for brain fog. I did see libido improvement but it wasnā€™t mind blowing back to normal. The brain fog was. Give it 30days and if you donā€™t see anything then I would stop taking it unless it is helping your depression\anxiety.

#31

5htp effect on libido all depends on the person. Look at this poll half found it raised it the other half found it decreased. Serotonin is involved in libido. It appears you need the right balance.

forum.bodybuilding.com/showthrea ā€¦ 644&page=1

#32

Serotonin and 5apha link

Serotonergic 5-HT2A receptor stimulation induces steroid 5alpha-reductase gene expression in rat C6 glioma cells via transcription factor Egr-1.
Morita K, Arimochi H, Her S.
Source

Department of Pharmacology, Tokushima University School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan. km@basic.med.tokushima-u.ac.jp
Abstract

Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of depressive mood disorders and well known to inhibit the reuptake of neurotransmitter serotonin into nerve terminals. Thus, it seems conceivable that these drugs may induce the outflow of serotonin from the synapse as a consequence of inhibiting the reuptake, resulting in the stimulation of glial cells surrounding nerve terminals. On this hypothesis, the effect of serotonin on steroid 5alpha-reductase type 1 (5alpha-R) gene expression in rat C6 glioma cells was examined as one of the in vitro model experiments for investigating the indirect influence of SSRIs on glial cells. Serotonin elevated 5alpha-R mRNA and protein levels through the stimulation of serotonin 5-HT2A receptors, and also elevated Egr-1 mRNA and protein levels prior to 5alpha-R gene expression in the glioma cells. Furthermore, serotonin failed to significantly increase 5alpha-R mRNA levels in the cells preloaded with the antisense oligodeoxynucleotide targeted on Egr-1 gene. These results indicate that serotonin may stimulate 5alpha-R gene expression via transcription factor Egr-1 in glial cells, thus suggesting that serotonin flowing out of the serotonergic synapse may be implicated in SSRI-induced changes in neurosteroid metabolism in brain.

PMID:
15936112
[PubMed - indexed for MEDLINE]

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#33

IhateFin, TIm any updates? Like I said I didnā€™t see any progress for a month but it would be good for you guys to post weekly updates.

#34

Not much to report. very slight improvements if any. One thing I will sayā€¦ I donā€™t know if anyone has this sensation - but it feels like a tingling in the brain almost. i associate it with brain fog as it feels like something just turned off up there. i feel like that might be slightly less present. but iā€™m still in brain fog world. might add some other things soon.

#35

I have had the tingling, it feels nice. It hasnā€™t touched my brainfog so far.

#36

Dont add anything untill your trial is over its only been a couple of weeks. Give a month to fairly asses it.

Thanks for updating guys.

#37

Since it took me about a month to see the effects I am thinking this could be similiar to an SSRI which takes 4-6 weeks to see itā€™s effectiveness. I also read a study that stated it took at least a month for serotonin enhancing substances to enhance memory. I think 6 weeks would be a fair trial.

#38

Is it work the same way like SSRI? if it so it could be good alternative to treat premature ejaculation.

#39

5htp is a natural amino acid in the body that converts into serotonin. SSRIā€™s do not make more serotonin they alter the brain to prevent it from recylcing it. In theory 5htp should work for this but who knows.

#40

FJ929, by chance, did the brand of 5-htp you took have St. Johnā€™s Wort in it? I ask because some people also claim relief from brain fog after taking St. Johnā€™s Wort, and many brands of 5-htp contain St. Johnā€™s Wort.