What causes testicular pain?

[thismightbegood]

Ever since being on FIN and quitting I’ve experienced a recurring testicular dull throbbing.

What are the theories of the mechanism/cause of this? Very curious what the general opinion on this is.

[Mew]

On Fin – most likely upregulation of testicular Testosterone production by 15-20%, since T which would normally convert to DHT can no longer due to Fin. Body senses this so increases T production to compensate. Unfortunately most of the extra T aromatizes to estradiol, hence gynecomastia, weight gain, etc.

Off Fin – no idea. It went away for me within weeks of quitting, however if T levels have dropped significantly and there is atrophy of genital tissue, perhaps that affects the testes in a negative manner at a cellular level as well. The drug is known to atrophy the prostate and seminal vesicles, both of which are part of the male reproductive system.

[spstriken]

@Mew

On Fin – most likely upregulation of testicular Testosterone production by 15-20%, since T which would normally convert to DHT can no longer due to Fin. Body senses this so increases T production to compensate. Unfortunately most of the extra T aromatizes to estradiol, hence gynecomastia, weight gain, etc.

Off Fin – no idea. It went away for me within weeks of quitting, however if T levels have dropped significantly and there is atrophy of genital tissue, perhaps that affects the testes in a negative manner at a cellular level as well. The drug is known to atrophy the prostate and seminal vesicles, both of which are part of the male reproductive system.

Mew this 15 - 20% increase comes from the protion not converting to DHT. The pain , I think is from binding of leydig cell by fin I have no study to support but have study to support for SP.

[proscarred]

@spstriken

@Mew

On Fin – most likely upregulation of testicular Testosterone production by 15-20%, since T which would normally convert to DHT can no longer due to Fin. Body senses this so increases T production to compensate. Unfortunately most of the extra T aromatizes to estradiol, hence gynecomastia, weight gain, etc.

Off Fin – no idea. It went away for me within weeks of quitting, however if T levels have dropped significantly and there is atrophy of genital tissue, perhaps that affects the testes in a negative manner at a cellular level as well. The drug is known to atrophy the prostate and seminal vesicles, both of which are part of the male reproductive system.

Mew this 15 - 20% increase comes from the protion not converting to DHT. The pain , I think is from binding of leydig cell by fin I have no study to support but have study to support for SP.

sps,
He makes perfect sense: the testicle is working overtime to produce more T as it senses that DHT is low and is trying to compensate. Your explanation makes no sense.

I still get this throbbing 5 months post fin. I would surmise that it is a spike in LH signaling for the testicle to produce more T. LH works in a pulsating manor, so that may explain why this comes and goes.

[spstriken]

@proscarred

@spstriken

@Mew

On Fin – most likely upregulation of testicular Testosterone production by 15-20%, since T which would normally convert to DHT can no longer due to Fin. Body senses this so increases T production to compensate. Unfortunately most of the extra T aromatizes to estradiol, hence gynecomastia, weight gain, etc.

Off Fin – no idea. It went away for me within weeks of quitting, however if T levels have dropped significantly and there is atrophy of genital tissue, perhaps that affects the testes in a negative manner at a cellular level as well. The drug is known to atrophy the prostate and seminal vesicles, both of which are part of the male reproductive system.

Mew this 15 - 20% increase comes from the protion not converting to DHT. The pain , I think is from binding of leydig cell by fin I have no study to support but have study to support for SP.

sps,
He makes perfect sense: the testicle is working overtime to produce more T as it senses that DHT is low and is trying to compensate. Your explanation makes no sense.

I still get this throbbing 5 months post fin. I would surmise that it is a spike in LH signaling for the testicle to produce more T. LH works in a pulsating manor, so that may explain why this comes and goes.

where did u get this idea? have any study? SP is the same as fin. it is also used in so many products to increase T just by simply stopping T conversion to DHT. so if fin increases T by increasing LH ,we who have now low T level should eat more fin to increase LH and then increase our T. I am not going to argue any more. Maybe I am wrong.

sps

[Mew]

we who have now low T level should eat more fin to increase LH and then increase our T.

What kind of twisted logic is this? Do you even realize what you are proposing? Nobody around here is interested in taking 5AR inhibitors ever again. Suggesting such ideas is pointless, and will likely raise the ire of other members, myself included.

[John_123]

@Mew

On Fin – most likely upregulation of testicular Testosterone production by 15-20%, since T which would normally convert to DHT can no longer due to Fin. Body senses this so increases T production to compensate.

Interesting theory. However, shouldn’t for example body builders who cycle testosterone then also experience testicular pain when they go off-cycle, and the body’s natural T production kicks in again?

Also, isn’t is strange that the testicular pain may last for several weeks, when the time for the T production to increase does not take as long.

Finally, T-production fluctuations of 15-20% (within a period of some days) can happen normally in men, for causes such as sleep quality and stress level, and then there is no testicular pain experienced.

I’m not saying increased T-production cannot be the reason finasteride causes testicular pain, however based on the above I find it more likely that finasteride causes testicular pain by some other unknown mechanism.