This looks interesting.
http://if-pan.krakow.pl/pjp/pdf/2012/5_1259.pdf
https://www.nature.com/articles/ijir201338
http://www.cpn.or.kr/journal/view.html?uid=975&vmd=Full&
https://www.sciencedirect.com/science/article/pii/S0149763417306450
I will give this a shot.
May be we became depressed because some kind of delayed onset of action on anti depressant effect.