The molecule that is formed when finasteride binds to the 5 alpha reductase II enzyme is called dihydrofinasteride. Can anyone test for this ish?
Does it mean that Finasteride is not destroying 5 alpha reductase enzym but is binding to the molecule? Term “inhibitor” does not particulary mean that 5 apha reductase is destroyed, but I always thought it is actually temporary killing this enzym.
I found something about that:
pubs.acs.org/cgi-bin/abstract.cg … 3069t.html
Something also very interesting is the fact that finasteride inhibits 5 alpha reductase type 1 (in the skin), this is something I did not know before.
Anyways, the mechanism of action seems not to interfere with the 5 alpha reductase resources, rather with binding to the molecule.
It binds to the 5AR enzyme, hence inhibiting it that way.