Before, during and after my use of finasteride (been off for 10 years) i have tried many functional and recreational drugs, mostly research chemicals. That’s how i found out how some stimulants are the only way to experience my pre-PFS libido.
“It is likely that dopamine can trigger penile erection by acting on oxytocinergic neurons located in the paraventricular nucleus of the hypothalamus, and perhaps on the pro-erectile sacral parasympathetic nucleus within the spinal cord.” (Source: pubmed)
In particular, the research chemical 3-fpm, beyond a certain treshold dose, brings back the old urges in full force, to the point of hypersexuality. The drug works as a releasing agent for dopamine and norepinephrine, increasing their concentrations in the synaptic clefts of neurons in the brain.
I’m not recommending anyone to go this route as the addiction potential is, understandably, not to be underestimated.
But i feel like there’s something to be learned from the mechanism of these dopamine releasers in search of a better, sustainable treatment. Speaking for myself, combining this drug with a PDE5-inbitor brings me as close as possible to normal sexual function but it is not a long term solution and could actually make things worse in the long term.
So, would there be safer medication options creating the same effect? I’ve been suggested dopamine agonists like pramipexol/cabergolin but the reports on this forum have not been promising.
More imporantly, as i can go from zero libido to 100% using a stimulant, is there anything to be learned from this by scientists and medical professionals for the possible treatment of our condition?