For me i KNOW this to be true
I have high SHBG and high E2. Youād expect lowered sexual function / penis atrophy.
Letās see what happens when i address that.
TS, the complicated thing for some is that their DHT readings are ānormalā. Here, there is a problem with DHT metabolism. Same issue really but difficult to address in practice.
Yes. It should be a surprise to no one (especially doctors and M*rck) that Finasteride can damage the penis and cause erectile dysfunction. Noone should doubt that has happened. HOWEVER if it was just erection problems this website would be a lot simpler. The problem is that an unknown number of men have also experience mental and physical side effects that are unexpected; brain fog, chronic fatigue and even muscle loss, despite normal testosterone levels. Also, yes, alterations to the Androgen Receptor by epeginetic means is a bit āout thereā, but few (viewtopic.php?f=27&t=4695) other explanations can possibly exists.
Is fibrosis ever reversable??? Have a read of:
Amelioration of Penile Fibrosis: Myth or Reality
andrologyjournal.org/cgi/content/full/31/4/324
(^colin, that is the most random post I have ever readā¦)
Itās very reversible in a timeframe as short as a couple days. I donāt think tissue has been replaced but itās being deprived of what it needs.
Unforrtunately its not as simple as lack of androgens cause damage.
Some people have only taken the drug for a few days and had the same crash afterwards. Also many people do just fine on the drug. So that leaves an acquired androgen insensitivity - either due to increased metabolism or due to epigenetic reasons or both.
Metabolism changes maybe. Usually due to a downregulation of the cortisol production line IMO.
Iām not buying the androgen insensitivty just yet. How many guys have completely ironed out ALL their levels before concluding this? Hormones are bloody complex and can require ALOT of trial and error to fix distorted levels.
Most people are just on this wagon to help use an excuse to do nothing (not consciously, but more from mental concession). Okay, perhaps that is harsh, but barely anyone on here will have adequately assessed their DHT metabolism (looking at uninary analysis and 3-diol-G!) and tried to redress this by assessing their preg/prog/cortisol levels in conjuntion with this. Also, many need to boost their throid hormones (T3/T4).
Since most endos dont have a clue about this, alot of posters arenāt making systematic efforts to fix themselves as per above.
Iād rather take things by the scruff of the neck and do what i can.
please, please, please - why has preg/prog/cortisol got anything to do with this? No endo has a clue about this because its TOTAL FANTASY.
I donāt think so: musclechatroom.com/forum/content.php?117-hormone-modulation-therapy-101
My preg is 6 (minimum is 40), and I was prescribed Progesterone even before this test was made. My cortisol is low normal for morning.
The cortisol-production-line looks like the grandmother of all the system.
This is written by someone who isnt an academic or a doctor, he doesnt quote any references and there are no real life examples as any proof of what he says - in other words, its useless. It is not a valid source of information, anybody can make anything up!
Anyway, NOWHERE does he mention how ātestosterone metabolismā is increased with cortisol. If you like his ideas perhaps you can explain how EXACTLY āboostingā preg/prog/cortisol is supposed to help make testosterone or DHT work. If nobody can do this please stop going on about it - it is very misleading.
It would be a much better idea to go read about some real endocrinology rather than learn stuff that is made up (and then actually take a hormone treatment that someone else has made up and then misapply it to our situation!).
He does use references.
Endos? You actually have the gall to talk about endos? Most donāt have a clue how finasteride works let alone DHT metablism and even less again about cortisol production line optimisation. Dr Crisler will tell you himself how clueless most of his peers are in this field. It just isnāt their domain (it should be, but they never learnt it).
Itās used alot by certain doctors.
A certain doctor took finasteride himself and developed high e2. He took progesterone and cured himself.
How about YOU go and do some reading?
Go get your bloods done and come back to me.
Lastly, plenty of people from Dr Crislerās forum supplement preg to great effect. Dr C is an advocate (case by case basis, obviously)
No he doesnt .
No it isnt.
No they are not. No he isnt.
I hope that chart you keep on posting isnt the sum of your knowledge - that would be embarrasing. I will re-post the question again, if you cant answer its because you havent got a clue what you are on about;
Read up on it before asking ME questions, please.
Iām not going to take the time to explain anything to you if you are using such hostility. Remember, Iām just trying to help.
musclechatroom.com/forum/content.php?121-baldness-and-prostate-101
That link has 7 or 8 seperate refences. Thereās also other posts with references to several highly esteemed doctors talking in detail about the important of progesterone etc.
So as i said, YOU do some reading instead giving me grief.
And lastly, GTFO telling me im wrong about people using preg or Dr C using ir. That forum BELONGS to Dr C and he have said this HIMSELF. So dont waste our time contradicting me when you donāt know my source (first person!!).
As for that flow-chart. Why downplay it? Have you actually looked at it in conjunction with blood results? It shows the critical connections between all the related hormones. That chart is fucking gold.
Donāt litter this place with your ignorance. All im doing is given people the chance to research this for themselves.
Heres a thread frmo a poster whoās had e2 issues for a long time. musclechatroom.com/forum/showthread.php?17212-preg-causing-nightime-sweets He takes prog/preg and they helped his e2 get tapered down immensely. This isnāt made up shit so im expecting an apology.
Actually its up to you to provide evidence for everything you say. If that, unsourced and based on nothing but FANTASY, theory that makes no sense whatsoever that you have now posted is really what you believe then there really is no point discussing this point anymore. But I look forward to hearing Dr Crisler state this as his own theory 
(ps colin, your not helping)
You clearly didnāt read any of my post. Letās not converse.
The information about cortisol down-regulation is summarised by Dr Thierry Hertogueās lectures musclechatroom.com/forum/content.php?118-cortisol-boost-101
Chillin thinks propecia down regulates our cortisol and thyroid reducing our overall metabolism. musclechatroom.com/forum/showthread.php?16220-Reasons-for-Male-Pattern-Baldness/page7
The potential treatment is to slowly add TD pregnolone and once cortisol is boosted add t3 in incremental doses by a very small amount.
You want real life examples? JN increased his cortisol and then added T3 and has declared himself recovered.
I have been suffering from propecia symptoms for 5 years. I have been added TD pregnolene in the last 3 days and my metabolism is increasing along with my erections (my cortisol levels). I will the add t3 once my cortisol levels are boosted.
Keep us updated, mate.
Itās not an exact science obviously but theres CLEAR merit in the whole thing.
Oscar, just for the record, not only is there evidence which you keep ignoring, Chillin is an exceptionally bright fella. You seem intent on getting to the bottom of things. Well, to do that youāll need an open mind and NO ego.
If you follow the link and read what is said in the first few paragraphs you will see that Chilln is in fact openly putting his own spin on these lectures, like the fact it has anything to do with a āproduction lineā or the fact the thyroid is involved. So, NO, what Chilln is saying is certainly NOT summarised in those lectures.
Forgive me, but I dont care what this Chilln fellow says. Hes not a doctor or an academic. You (or I) have NO IDEA if what he says is true or not - thats just common sense, nothing to do with egos, its called being scientific. I would be interested to know what exaxctly is meant by āmetabolismā in this context.
This is an actual video from Dr Hertogue on Cortisol (he says just take Cortisol and high Cortisol is bad for T levels!) youtube.com/user/HertogheMedschool#p/u/8/pUqjOXeoFRo
I have actually noted a group of sufferers that have had very positive experiences using corticosteroids: viewtopic.php?f=27&t=4695&p=33052#p33052
My symptoms have healed after suffering since 2005
please elaborateā¦ what symptoms and to what degree?? ed, shrinkage, muscle loss, brain fog etc etc??
Any info would be greatā¦
I have read similary studies, yes not theories and by these are the most scary and undeniable truths. So if scar tissues have developd what options are left for us?
And I dont think scar tissues are limited to our penis only they must have developed to our body parts as well depending on DHT concentration there. I wonder if our Gyno is the real gyno not fat and scar tissues. The only way to verify these hypothesis we need biopys of different body parts. I hope Aworās team is looking for scar tissues as well.