Where are you from (country)?
How did you find this forum?
Google Search - Post Finasteride Syndromme
What is your current age, height, weight?
30, 174cm, 65kg
What specific drug did you use (finasteride, dutasteride, saw palmetto, etc…)?
Finastopic (Minoxidil 5% + Finasteride 1%)
What dose did you take (eg. 1 mg/day, 1 mg every other day etc.)?
Finasteride 1mg - Everyday
Finastopic (Minoxidil 5% + Finasteride 1%) 1ml - Everyday
What condition was being treated with the drug?
For how long did you take the drug (weeks/months/years)?
Finasteride 1mg - 2.5 years
Finastopic (Minoxidil 5% + Finasteride 1%) - 10 months
How old were you, and WHEN (date) did you start the drug?
Finasteride 1mg - 27 years old, December 2016
Finastopic (Minoxidil 5% + Finasteride 1%) - 29 years old, July 2019
How old were you when you quit, and WHEN (date) did you quit?
Finasteride 1mg - 29 years old, May 2019
Finastopic (Minoxidil 5% + Finasteride 1%) - 30 years old, May 2020
How did you quit (cold turkey or taper off)?
Finasteride 1mg - Cold Turkey
Finastopic (Minoxidil 5% + Finasteride 1%) - Taper Off
How long into your usage did you notice the onset of side effects?
What side effects did you experience that have yet to resolve since discontinuation?
[X] Loss of Libido / Sex Drive
[X] Erectile Dysfunction
[ ] Complete Impotence
[X] Loss of Morning Erections
[X] Loss of Spontaneous Erections
[X] Loss of Nocturnal Erections
[X] Watery Ejaculate - PARTIALLY RECOVERED
[ ] Reduced Ejaculate
[ ] Inability or Difficulty to Ejaculate / Orgasm
[ ] Reduced Sperm Count / Motility
[X] Emotional Blunting / Emotionally Flat - PARTIALLY RECOVERED
[X] Difficulty Focusing / Concentrating
[ ] Confusion
[ ] Memory Loss / Forgetfulness
[X] Stumbling over Words / Losing Train of Thought - PARTIALLY RECOVERED
[ ] Slurring of Speech
[X] Lack of Motivation / Feeling Passive / Complacency
[X] Extreme Anxiety / Panic Attacks
[X] Severe Depression / Melancholy - RECOVERED
[ ] Suicidal Thoughts
[X] Penile Tissue Changes (narrowing, shrinkage, wrinkled)
[ ] Penis curvature / rotation on axis
[ ] Testicular Pain
[ ] Testicular Shrinkage / Loss of Fullness
[X] Genital numbness / sensitivity decrease - PARTIALLY RECOVERED
[ ] Weight Gain
[X] Gynecomastia (male breasts)
[X] Muscle Wastage - PARTIALLY RECOVERED
[X] Muscle Weakness - RECOVERED
[ ] Joint Pain
[ ] Dry / Dark Circles under eyes
[ ] Prostate pain
[X] Persistent Fatigue / Exhaustion - RECOVERED
[ ] Stomach Pains / Digestion Problems
[ ] Constipation / “Poo Pellets”
[ ] Vision - Acuity Decrease / Blurriness
[ ] Tinnitus (ringing or high pitched sound in ears)
[ ] Hearing loss
[ ] Increased hair loss
[ ] Frequent urination
[X] Lowered body temperature - RECOVERED
Other (please explain)
[X] Lack of brain-penis connection - PARTIALLY RECOVERED
[X] Uncomfortable burning or numb sensations on the penis - PARTIALLY RECOVERED
[X] Prominent veins with painful/uncomfortable sensitivity on the penis
[X] Low Energy - RECOVERED
[X] Low Mood - RECOVERED
[X] Difficulty to deal with frustration (anxiety) and to relax after stressful situations
[X] Anhedonia - PARTIALLY RECOVERED
[X] Inability to rest regardless of the number of sleep hours - PARTIALLY RECOVERED
What (if any) treatments have you undertaken to recover from your side effects since the discontinuation of the drug?
- Tadalafil 5mg (every second day)
- Acetyl L-Carnitine 1000mg (3 times per day)
- L-Arginine 2000mg (3 times per day)
- Healthy and varied diet (vegetables, fruit, fish, etc.) trying to keep carbs and sugar low
- Strict sleeping routine (8h, same time every day)
- Moderate/High Intensity Sport at least 4 days per week (Running and weightlifting)
- Simplify and structure daily routine following the same every day
- Sodium Butyrate 600mg (twice per day)
If you have pre or post-drug blood tests, what hormonal changes have you encountered since discontinuing the drug (please post your test results in the “Blood Tests” section and link to them in your post)?
June 2020 Hormone Panel
- Liver irregularities for first time in my life. High bilirubin and low transferrin even though iron is mid-range.
September 2020 Hormone Panel
- Additonally, Vitamin D3 has low.
Tell us your story, in your own words, about your usage and side effects experienced while on/off the drug.
My story with the drug is atypical because I took oral Finasteride 1mg for almost 3 years with mild symptoms (mainly sexual, libido and erections) which gradually worsen. Mild gynecomastia began to be an issue and new purple and prominent veins appeared on my penis; inflammation sensation on them followed until I decided to quit the drug cold turkey. I had a few days in which I had higher libido and close to full erections for 2-3 days and suddenly my whole baseline decreased and stayed the same for 2 months. This is when I believe I had my PFS crash.
My doctor suggested trying topical Finasteride (1%) with Minoxidil (5%) to preserve my hair as the topical solution should not give me any sides due to its poor systemic absorption. Big mistake.
On the first months, I did not notice any further sides and the effect on hair was better than while on the pill. After 7 months of use, I noticed that I did not have low libido but any libido at all. Moreover, my erection became weaker (being for the first time not always functional) and I was not able to concentrate properly at work. I decided to stop the treatment, this time tapering off at a reduced dose.
A few days after eliminating all drug from the system, everything became much worse, particularly in the cognitive department. I lost all ability to focus, I had no motivation to even do my hobbies, I felt the energy of an 80-year-old person, I could not get up from bed in the morning because I was waking up extremely tired regardless the number of hours. Funny enough, the tiredness only used to last 15-20 minutes since I was able to stand up from the bed and begin my daily activity.
I had to leave my career in investment analysis and, up to date, I have not been able to try it again because I cannot read a full-page and be focused in something for more than 2 minutes.
However, not everything is a hopeless post of bad news. Since July 2020 I am under the supervision of a doctor with experience in PFS in Amsterdam (protocol above) and have made significant improvements concerning mood, energy and sleep improvement. Running is being a game-changer for me. There is still a long run towards being a functional person again but I do not feel miserable anymore and that is a BIG difference because I can be much more rational towards the disease.