How that? Did you do anything in special, like dieting or exercising, changing lifestyle, etc?
Yeah I got in the best shape of my life, waking up at 5:30 AM to do HIIT and all that stuff.
But I got hit with even worse problems a second time years later from another drug and can confirm in retrospect that this strategy had no effect. Thereās been zero correlation since between my rate of improvement in any area and how healthy my lifestyle is.
Itās actually the other way around. The better I get, the more I can exercise and the more disciplined I can be regarding diet and everything else.
I donāt really visit much these days because I am much better. Not 100% cured, but letās say 70% both mentally and sexually. Good enough to function throughout my day to day life without thinking that I have PFS or am much hampered by it, which is the goal I guess.
Penis sensitivity is at like 80% so really good lately. Libido can still be somewhat dodgy. As to what brought these improvements it is very hard to say, because Iāve used SO much stuff.
Just in the past 2 years I did:
- several cycles of HCG at 250 IU / day, few months in total
- 200 mg of Proviron for a week
- 11-keto DHT at huge suppressive doses (20 mg / day)
- Tamoxifen for PCT after these androgens
- Raloxifene to combat some gyno I had
- Exemestane at 25 mg / day for a while
- Used celery root powder for my Thyroid issue, this was initially estrogenic but then seemed to increase my DHT baseline
And I probably canāt even remember everything. The only common thread between all these substances is that they modulate and shift hormones one way or another, sometimes extremely, and my guess is that this forces the body to recalculate and try to maintain homeostasisā¦ given enough effort it finds a new baseline which is closer to normal.
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Iām still pretty sure the numbness is caused by wrong interpretation of incoming signals in the brain. Has anyone studied the topic of how this mechanism actually works?
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I have recovered from numbness with aromasin and arimidexā¦ for Ed I have to use regular cialis and manual stimulation ( urologist says I developed venous leak because of pfs)
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Thatās really so scary because how the hell do you fix something like that?!?
Jesus
How did you access these?
I have long wondered the same. Does anyone really know what arousal or libido is and how it works, from a biochemical perspective?
They know a lot about the biochemical steps that lead toward an erection, with the assumption that the erection is all that matters and once that is achieved you have everything. But as far as I know pretty much nothing is really known about the process that induces arousal, libido, erotic sensation, that sort of thing.
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Iām definitely missing some link in that complicated connection. Achieving erection seems like a pure mechanical process, not connected with arousal and any erotic sensations anymore.
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Same boat here. Purely mechanical experience.
Yep !
Brother can you give me some advice, Im struggling hard here. I have to take letrozole pretty much everyday, Its the only thing stopping me from turning into a woman. Tried so many stuff. Regardless of what i use, at the end of the day i still have to take letro
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Hereās what Iāve been able to figure out:
- I read somewhere on Wikipedia that arousal (lust) comes from dopamine hitting a certain area of the brain.
- If Iām not mistaken, dopamine is released in a number of situations including when we feel pleasure
- This makes sense to me: we all know that when we feel sexual pleasure, we get more aroused (for example: masturbation).
- Iām a special case where finasteride made most of my penis numb (unable to feel pleasure), but there is still one or two parts that are still able to feel pleasure (not numb).
- Fascinating observation: depending on the part of my penis being stimulated, I feel either pleasure (resulting in growing arousal and erection) or no pleasure (resulting in disappearing arousal and erection). Let this sink in: depending on the part of my penis being stimulated during sex, I either feel like a typical PFS patient or like a normal, healthy, (more or less) PFS-free man. All it takes is stimulating a different tissue in my genital area! Isnāt that crazy?! (I communicated this insight to Dr. Melcanghi)
- Therefore, I am convinced that if a way was found to restore sensitivity in the numb parts of our penises, weād largely cure the sexual side of PFS. I see further evidence in the fact that finasteride not only switched off sensitivity in my glans, but also smegm production, so itās a localized cell issue. Just like for some people the skin is affected (numbness and sebum a.k.a. oil production).
I have made other observations but this one is the one that is important for our community. I hope it helps.
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Itās a delicate combination of three things:
- Hormone balance (assuming properly functioning receptors);
- Brain chemistry (NT/NS balance); and
- Vascular function.
As for the sensitivity of different areas of the penis, some are just more sensitive than others, and with PFS those baselines just get reduced, leaving many sufferers with either no sensitivity in the entire penis or just some sensitivity in areas like the head/underside. This can leave the rest of our shaft either totally/virtually numb.
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This is not my experience. Iād say that my penis has lost almost all sensitivity (itās so bad that manual stimulation doesnāt get me an erection). YET when I had penetrative sex with my last girlfriend, with a condom, and thrust deep, the traction on the penis skin (just below the head, could be part of the foreskin, Iām not sure - Iām not circumcised) creates as much pleasure/arousal as before PFS.
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A very important bump
Seeking ANYONE who recovered 100% from numbness and maintaining erections
My dicks completely numb from Finasteride, however ive found when i have methamphetamine all my sensitivity comes back 10 fold. So much so that if my girlfriend even just touches it with one finger, the pleasure is through the roof, including arousal and libido. Which tells me the nerves arent damaged, they just arent functioning or firing.
Methamphetamines directly boost dopamine, so i think dopamine is a big part of the puzzle.
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Youāre saying you literally go from zero to 100% just from dopamine being increased?
Its only an assumption, there could be something else at play biologically speaking.
But I read methamphetamine directly boost dopamine, bypassing other pathways.
There is also the allopregnanolone/dopamine study which points to finasteride lowering dopamine.
My neurotransmitter test came back low dopamine and low seratonin also.
Its probably not the only piece of the puzzle but i think its definitely relevant and why i mention it for everyone.
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Iāve often thought that myself
Or maybe itās a multi thing
Because ppl with pssd have the sane issue but it might be fit different reasons
Or not who knows