One Hint: Pituitary Gland… I have a feeling this is also part of the puzzle…the brain isnt working as it should.
I’d say all of this stuff is just pointing more and more to auto immune disorder targeting androgens or possIbly the anfrogen receptor Itself. BTW I just popped 14, 000 iu of vitamin d 3.
Vitamin D[Size=4]3[/size] works synergistically with progesterone to restore brain function. en.wikipedia.org/wiki/Progestero … treatments
God who knows how low my vitamin d was when I came off if it’s this low now.
Its amazing the amount of men here who are vit d deficient. This has to do something with pfs.
Seems to be a recurring pattern, similar to reported loss of response to androgens in many men post-drug.
Probably not coincidental considering both androgen receptor and Vitamin D receptor are both members of the Nuclear Receptor Superfamily (which includes others as well)
my vitamin d was the same before and after propecia… not that high…
Growth Hormone is supposed to be very very low. en.wikipedia.org/wiki/Growth_hormone_deficiency IGF is used as an indirect measure of GH.
The ‘Gold Standard’ for determining the integrity of the hypothalamo-pituitary-adrenal axis and GH response is an Insulin Tolerance Test. Ask your endocrinologist!
Second Amendment…thats all part of my theory…low levels of vitamin D = low progesterone. low progesterone causes estrogen dominance…estrogen dominance premotes histamine release.
Propeciashiz- very interesting…no extremely interesting that you had very low vitamin D before propecia. I am going to go out on a limb and say that your progesterone could have possibly been low. Now for others that scream they have high progesterone…cortisol blocks histamine receptors so even in if you test normal to high, your actuall levels can be low.
Dr. Brian Skop:
14815 San Pedro Avenue San Antonio, TX 78232
(210) 493-6824
I don’t think there are many of you in Texas but this idiot’s opinion is that we all have “mania” and are obsessed with our numb penises. He’s a psychiatrist who disregards all facts that Propecia causes any mental problems… Dr. Irwig, Dr. Traish and Dr. Jacobs should all personally write him… and educate him.
It is interesting that you write that. When I saw Dr. John Muhall in Manhattan, he said he could not tell me what PFS was, but he said that many men seem “obsessed with their penis’s” I honestly did not know how to respond to that comment.
I saw Muhall too over a year ago… complete and utter waste of time he doesn’t believe in PFS, even though he respects Dr. Jacobs.
Idiot doesn’t realize the condition effects the entire body.
The only difference is that Skop actually hurt me with his complete lack of knowledge about NOW WIDELY known finasteride side effects. Feel free to write him including copies of Dr. Irwig’s and Dr. Traish’s studies. I would myself but I can’t… would be better coming from other sufferer’s.
Gents:
My 3-Adiol-G 22 months off Finasteride is still in the toilet.
3-Adiol-G: 275 (260-1500) (09/18/2012)
Unbelievable.
What level was your DHEA?
Its always been normal-ish. DHEA isn’t the issue here… androgen metabolism is clearly screwed up along one of the major pathways. And I seriously believe we have 5-alpha reductase auto-antibodies floating around in us causing all this shit…
WE NEED TO FIND A CURE FOR THIS SHIT ASAP!!!
Well guys I’ll still be touch with those you who have my contact info but I have to take a break from my finasteride activities somewhat. I have been trying to push ahead with getting our cause out there so much that it has consumed my life somewhat. It didn’t help that I became so involved with the problem for my past relationship and for my career which I am struggling to rebuild. Gonna step back a bit and try as best I can to “live” for awhile.
I don’t think I can do this much longer. If I do “end it” one of these days I hope you guys have the courage and perseverence to keep going forward. I know its the propecia induced depression talking but I’ve lost my entire life and waiting another 10-20 years for a cure just isn’t worth it to me anymore.
hang in there. Don’t loose hope.
Why? Look at all the attention we have garnered and nothing… I just keep losing.
I’ve alwayd thought of this thread as a personal journal for myself logging everything that has happened to me… my thoughts and feelings throughout the last two years battling this shit. Every small victory preceeded by a larger, personal, defeat.
When my GF kicked me out of the apartment and ended our relationship, two weeks later I was demoted and finally allowed to go back to work. I called her for some emotional support… three days later after no response I got an email from her saying she was dating one of her co-workers and to leave her alone.
Even she who tried to help me through everything eventually turned her back on me and left me. My parents who sit up in NY do nothing. My father who could have been an advocate for me when things were truly bad, instead decided to keep my “condition” private… as if privacy even matters after the things many of us have been through. Nearly everyone in my life close to me has either turned their back on me or done nothing to help me.
The government could have offered me a position that would have only been. $15, 000 pay cut… instead they gave me a job paying less than half what I would have made before. They didn’t demote me because they actually thought I was sick… they didn’t do it because of liability even… they did it to punish me. Why? Because almost no one on earth understands PFS. To them I was just some asshole probably making things up. Also being the only white guy surrounded by 5 hispanic managers probablh didn’t help either.
But in the end still things are what they are. The woman who at one time wanted to marry me is gone, my career has been totally ruined and my junk is still a mess on top of all that. Whatever happens from here on out I hope one day we have some form of redemption granted by the scientific proof that this is a “real” disease.