Ethanol Enhances Neurosteroidogenesis in Hippocampal Pyramidal Neurons by Paradoxical NMDA Receptor Activation
I wonder how many of us still drinking alcohol ? Because I am not.
Its effect on neurosteroidogenesis is probably due to gaba-b agonism, same as baclofen and GHB which Iād really like to try. Look up ethanolās antiandrogenic effects on brain receptors though. I believe a bunch of people here have crashed following a booze bender.
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Maybe the small percentage of people that develop PFS are those who stop drinking, and those that continue somehow their brains readapted and continue producing neurosteroids.
I developed pfs in college and I was drinking most weekends and some week nights
But did you stop drinking ?
Hah. Letās drink to recovery! In all seriousness, a short term (few hours typically) recovery after a long night of drinking is a common theme among PFS, PSSD, and PAS patients.
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Is this drug safe?
I didnāt stop before or during my crash
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Pretty sure alcohol is GABA A. Not B. But I could be wrong. If you google GABA B agonist you will only find Phenebut, GHB, Gabapentin (sort of) , and its cousins baclofen and one other which escapes me. I think Ethanol is its own GABA A receptor. Seperate from the Benzo receptors. Thats why they use Benzos to wean people off of alcohol withdrawal. Different receptor. ( Once againā¦ āI thinkā LOL)
As for drinkingā¦ I quit for 6 months right after my initial crash. Then I started drinking againā¦ during the periods of drinking my head pressure and dizzyness almost completely resolved. Sleep seems to have improved a little bit. Muscle twitches improved moderately (almost none at this point and when they do happen they are very weak almost unnoticeable) Not sure if its related at all. Other things got worseā¦ vision. I also notice that I can literally feel my T start to tank if I drink 3 days in a row. especially with beer which is estronogenic . I can feel weakness in my legs by my knees. Vision gets moderately worse but temporarily. Stop drinking, fast for 36 hours, eat meats and do heavy legs and everything seems to improve back to baseline.