More research released today

[THETIGERSHULL]

@mcibofh

Even if research found something today to help us how likely is it that the FDA will bog it down. Merck got away with a weak ass clinical trial. I bet somehow they will find a way to screw us over again. I know most of us would jump at the chance to trail a fix but the FDA will step in to protect us.

Like you sarcasm

Hope your doing a bit better too buddy since our skype chat?

[mcibofh]

You know how it is. Ups and downs.

[awor]

@pvdl

An accomplished (High IQ) Doctor comments on this study:

“This is a a so-called open journal, ie there are no controlled peer review of the submitted work. The number of subjects studied is very small. The selected parameters require very many, completely unsecured assumptions about the pathomechanism of sexual dysfunction. In summary: The article does not prove anything. Except: There is clearly a growing community of people with sexual dysfunction (felt or real) after administration of finasteride, which manages to encourage scientists to place completely vague findings on this topic in the scientific literature. It is in this self-reinforcing collective madness, of course, an important link.” (Google Translator)

1. In the field of medicine, “accomplished” is often more a manifestation of good rhetorical skills and political savviness rather than of a specially high IQ
2. Why are you wasting your time and money with this guy? Find yourself another doctor and give him this book as a fare-well present: amazon.de/Die-wei%C3%9Fe-Maf … 3868832718

Here is some more Google translate for him (cover text of “The White Mafia”, see link above)

In our health care system prevail mafia conditions. In order to secure the profit of the physicians and the healthcare industry, unnecessary surgeries are performed and medications prescribed do more harm than good. Healthy are declared to be sick because laboratory values ​​arbitrarily determined not meet the standards or show X-ray images completely acceptable deviations from the ideal. The industry-oriented “medical self-government” refuses to respond to scientific findings, thus preventing the progress - especially when science threatens well-established business models. The multi award-winning science journalist Frank Wittig researched for many years in the medical use and is there met with scandalous states and a “white mafia” of the medical profession and industry, which relentlessly enriches itself on the healthy and the sick. Wittig reveals where there is suffering in the system, and provides guidance on how we reduce the patient in contact with physicians the risk of becoming a victim of the white mafia. A book that accuses arouse and enlighten. Because knowledge is the first road to recovery - of the system and their own health.

[davey]

Great post Awor. Here’s another good text which the “accomplished” doctor could be given:
amazon.co.uk/Bad-Pharma-How- … 000749808X

[Oscar]

The scientists gave three reasons in this paper for the higher AR expression in genital skin:

1. Locally reduced androgen levels due to 5a-Reductase inhibition.

2. Androgen deprivation has caused ‘ageing?’.

3. ‘Epigenetic’ change to the AR receptor itself. Something in the same category as prostate cancer.

---

Here is a radio interview by ‘Adam’ at PFS Global Support with Dr. Jindan Yu, M.B., Ph.D. who is an academic and expert on prostate cancer about the findings in this paper. blogtalkradio.com/pfsglobal/ … -jindan-yu

She clearly states the higher AR expression is likely due to reduced local levels of androgens and it isn’t a result of a change to the androgen receptor itself.

[Oscar]

We also estimated nerve density on hematoxylin and eosin stained slides. For this purpose, each nerve seen in the slide was counted as one. All the reported figures were the average of 25 different fields at 20× magnification. All evaluations were performed by an expert physicians blinded to subjects characteristics.

…

We demonstrated that cases and controls had similar nerve densities, thus no structural nerve alteration seems responsible for this kind of finasteride side-effect.

Essays on Peripheral Nerve Repair and Regeneration

P84 “Although very popular it must be emphasized that hematoxylin and eosin is not an adequate method for nerve tissue staining because the myelin sheaths are not labelled and are thus difficult to be detected.”

Neurotoxicology: Approaches and Methods

P9 “Many of these components such as axons, dendrites and myelin sheaths are not demonstrable with the common H&E stain.”

Neurons and Support Cells siumed.edu/~dking2/ssb/neuron.htm#3

“In routine H&E slides, peripheral nerves resemble other fibrous tissues like smooth muscle or collagen.
Unless specially stained, nerve fibers tend to appear rather pale. Neither myelin (which is mostly fat) nor axoplasm (which is mostly water) is readily stained by H&E.”