The company said in a statement that it does not know the drug’s exact mechanism of action, but “Vyleesi is believed to bind to melanocortin receptors in the central nervous system that are thought to be associated with sexual function.”
A lot of people posted about this drug years ago… and it’s finally going to hit the shelves.
'The melanocortins are involved in a diverse number of physiological functions, including pigmentation, steroidogenesis, energy homeostasis, exocrine secretion, sexual function, analgesia and inflammation." - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095696/
I wonder what role melanocortins have in our disease. Interestingly enough, some of us, including me, have reported pigmentation spots during PFS. I wonder if that is just a coincidence and has nothing to do with PFS. Or if we have excess melanocortins, or something else…
I know I’m critical of some of your posts, but thanks for sharing @MOONCHILD !
Definitely worth keeping an eye on.
Did not have a great effect on me.
@moonman1 Did you do a nasal spray analog of it or a subcutaneous injection? Was it legitimate product or something from the internet?
A PAS patient metntioned to me that he tried one of the melanocortin peptides he ordered over the internet and it worked for him. Only problem was that he said it provided easy erections, but not quite the same as having a real libido. May have used the phrase “it felt synthetic”.
I believe I’ve tried both PT 141 and Bremelanotide. Both were ordered via the internet. I’d be willing to test Bremelanotide again as I am in a very different state than I was in the past. I also encourage other PFSers to try it, my results don’t mean it won’t work for someone else.
does melanotan-2 count? i tried it…meh