Marijuana use in Propecia Victims

I’ve seen a number of threads and marijuana seems to be beneficial for you on all I read. Have you actually experienced problems from taking too much or dosing over a long period of time? I understand what you mean about xanax. Valerian root has similar properties and I liked it originally but gave me the spacey feeling you described after a while and over time stopped working. I know this is a path that the body doesn’t respond to anymore. Now it just keeps me awake while I get more and more tired.

What I’m excited about with marijuana is that I warmed up my entire body for days after taking a hit off a joint. My penis is warm and full. Sex the couple days after I took it was a pre fin state. But it’s not sex that had me so happy, it is feeling bodily normal, relaxed, interacting with life, seeing bright colors again, smelling things more clearly, enjoying interpersonal interaction. It really brought life back into me.

Vasodilation…

Well, for me, when I use androhard, I get all that you’re supposed to get from increased (or in our case normal) DHT levels. I feel…manly, like I used to, before fin. From libido, sexual thoughts, my old attitude of not giving a shit, harder, fuller erections, the way I interact socially with people…everything. But…there are still sleep problems. There is still the inability to feel completely and utterly relaxed. I can’t focus or think as “deeply” or as quickly as I once did. There is static in the lines, so to speak. These things are attributed to Gaba.

Gaba is the chemical that makes you feel calm, centered, focused, serene… Allo acts on Gaba to increase these feelings. This is what alcohol does. Increases Allo which in turn cranks up Gaba. A common side effect of PFS is that people can’t feel the pleasure associated with alcohol. It doesn’t take a scientist to figure out that somethings wrong there. It also doesn’t take a scientist to figure out that when you take a benzo, which acts directly on Gaba the way allo does, and you get very calm, relaxed, and are able to sleep, that there’s a connection there as well.

And, even though it’s completely subjective to me, I can feel the difference in myself when I play around with these things.

There’s a very good page in the “Mental Side Effects” section where somebody explains how disrupting 5arII can create negative neurosteriod profiles which can be very damaging. You should check it out. And, keep in mind, these are my observations about MY system. Some people have digestive issues, or other problems that I don’t have. These are things that work for me. And, based on the information we have available, it’s easy to see why they work.

Ofcourse. I know what you mean and i feel the same way. When something works for me im sticking with it, thats a no brainer. Good for you that you find a system for some relief and abit of life back!

I still think that your reasoning is abit weird. Alltho i can understand and i work the same way that i want to belive that i understand why some stuff makes me feel better when i take them it sort of puts me in control. Much needed since so many of the situations we are presented with our beyond our control in this mess, or so it seems right now.

But many of the substances that makes me feel better makes ppl with completely different issues than mine feel better too. Its like increasing T, its suppose to make you feel better according to litterature even if your not hypogonodal. Enhancing gaba to supra levels could possibly do the same but that doesent mean it was our issue to begin with just because it might eleviate some of our symptoms?

If i have a protocall thats working for me and its safe no way in hell would i change it so thats not what im on about, just so you know :smiley: Hope you continue to recover!

Not really sure what you’re “on about” but if you read the studies and the literature that are on this site, it should become very clear. And, this thread has veered way OT.

Study below: 9-thc beeing the active compound in marijuana.

Objectives
To determine if other abused drugs elicit alterations in brain neurosteroid levels, 9-tetrahydrocannabinol (9-THC), cocaine and morphine were administered to male rats.
Methods
Cortical brain tissue and plasma were collected and analyzed for steroid concentrations using radioimmunoassays.
Results
9-THC (5 mg/kg, IP) elevated cortical allopregnanolone levels to pharmacologically active levels, while morphine (15 mg/kg, SC) produced a small but significant increase. Cocaine (30 mg/kg, IP) did not alter allopregnanolone levels, nor did lower doses of 9-THC or morphine. Plasma progesterone levels were elevated in both 9-THC and cocaine-treated animals.
Conclusions
Some, but not all, drugs of abuse produce increases in cortical allopregnanolone levels. In addition, increases in plasma steroid precursor levels do not always translate into increases in brain allopregnanolone levels.

So do you think its reasonable to think that its the elevation in progesterone and the resulting increase in allopregnanolone that produces the possitive effects on us when smoking marijuna?

How many did try progesterone treatment thus far?

Marijuana has many active cannabis, which acts like a neurotransmitter and pain reducer. There is still a lot about the chemical compounds we don’t know.

[quote=“martinM”]
Marijuana has many active cannabis, which acts like a neurotransmitter and pain reducer. There is still a lot about the chemical compounds we don’t know. /quote]

Ofcourse yet here we have a study suggesting, no infact saying that thc the most active substance in marijuana in high dose does increase progesterone and thus allopreg and im asking if you guys think this might be the reason for some of the benefits reported with the use of Marijuana.

Do you think theres a connection with users on this site having reported elevated progesterone levels and the fact that some take a drug that does the very same thing and have possitive effects?

This is interesting to me because i tested high for progesterone on the day that i decided to test hormones when i was feeling good instead of the usual tests i do when i feel the worst. Progesterone obviously also lowers dht so its not like theres no connections here and saying theres alot we dont know gets us nowhere but speculating might get us somewhere.

Perhaps you have been discussing this increase in progesterone from certain drug use before and im just digging up stuff you allrdy know, if so i appologize but its tough to read through this entire site to check if things have allrdy been discussed. Especially since ive been so inactive on this site untill recently as i was feeling alot better than i do after my latest crash a couple of months ago. Just trying to catch up…

Increase in allopregnanolone would certainly increase feelings of well being and relaxation by it’s Gaba modulating effects. This alone would increase libido in some men who have worse neurosteriod problems then others on this stie. I believe this would certainly be a valid point. I know for me, my physical symptoms are gone. What’s left is neurological dysfunction which in turn effects my libido.

Sorry, Ipad changed cannaboids to cannibus on me. I agree that thc may be the main ingredient in many strains of marijuana, however it’s a cannaboid, and I think 60 have been identified in the marijuana plant, some don’t have any THC at all. And it’s only been effective in me at low doses, so I’m not sure how that affects your idea.

So there’s a lot more still to learn about the plant. Marijuana acts as a muscle relaxer and also a mental stimulant, in low doses, it alleviates anxiety. So yeah, the 'pregnalones could be causing some effect here, whether it’s the main one I don’t know. I can tell you that I’m much more relaxed now, the blood flows to my penis and it’s warm all the time and even gets hot when I have an erection. I’m leery of attributing all beneficial qualities of the plant to THC, because the medical industry is trying to do the same so they can get licensed to create thc extracts and sell them legally with motivation of continued banning of the plant. However THC is definitely not the only active cannaboid nor is it responsible for all of marijuana’s antioxidant effects.

I posted quite a bit of info about it here:

viewtopic.php?f=6&t=4363

The trap I want to avoid is attributing a single substance, an extract if you will, to the beneficial action. The human body is extremely complex, as is the plant. There are so many workings I don’t think we understand and would be foolish to attribute micro views to the macro results. Results are really what we’re after. I’m taking my experience as a gift, the plant brought my life back, and I hope it continues to do so.

FYI many marijuana users rotate strains and plants so they don’t get tolerence to any specific cannaboids. Some are better for pain management (indica) and some for mental problems (sativa).

Good info thanks!

Marihuana and its constitutents delta 9-tetrahydrocannabinol (delta 9-THC) and cannabinol (CBN) were tested for their ability to interact with the androgen receptor in rat prostate cytosol. Smoked marihuana condensate, delta 9-THC, and CBN inhibit specific binding of dihydrotestosterone (DHT) to the androgen receptor with a dissociatin constant of the inhibitors (Li) of 2.1-5.8 X 10(-7)M. in addition, other metabolites of delta 9-THC were also androgen antagonists. This data suggests that the anti-androgenic effects associated with marihuana use results, at least in part, from inhibition of androgen action at the receptor level.

ncbi.nlm.nih.gov/pubmed/6249575

I dont think its a fluke that pretty much everything we try and do have a dht connection, do you?

I want to ad a word of caution.

Me i have never been a guy that even wanted to try drugs. Ive been drugfree for all my life except alcohol and cigarettes and i dont touch alcohol anymore either. This one time when i was 15 or so i tested some weed but basicly dident feel anything good out of it so never had desire to try it again untill recently for pfs.

Exited by the good results of others in this thread i decided to try some weed (yesterday) and c if it could make me feel abit more relaxed. Things went from bad to worse pretty fast and i was having a fullblown panic attack for 3 hours untill it eventually faded away. It was actully so bad i was thinking of going to the psyciatric emergency care. Today im left with a clouded heavy head and that empty state (thats actully quite relaxing) of mind you get when your body goes into rest after an exhausting event. Hopefully ill be back to myself within a day or 2.

Just be carefull! i was an idiot for not micro dosing this to c what kind of effect it had on me.

Good point. I think everyone should do research on this. In my success I’ve only had luck when either micro dosing or eating it, eating being preferential for those with real medical issues like us. If you do research on this you will also find that there are many different kinds. Plants laden with TCH (the psychoactive stubstance) and little CBD are very likely to cause anxiety and a depressive state. People with nerve or pain issues tend to go for strains high in CBD and low in THC.

I’ve been on some MMJ message boards and there are many people with nerve problems that use marijuana as their only source of treatment. Most have said to me that eating has a much better effect on their nervous system in general, especially the relaxation effects.

I also tried some of a friend’s “skunk” about a year ago, which is high in THC content, had too much, and got paranoid for hours. It wasn’t fun. If you’re able to or in an area that allows for selection seek out an indica strain. Many of the pot clubs are breeding strains that are higher in THC content because they have a higher market value. Also check with your friends to determine the effects of the marijuana before consuming it, some strains are prone to anxiety. EDIT: There are also different types of the plant, stick to buds, mids, or fire, do not consume sticks and seeds!!!

I’d like to remind everyone to reevaluate the term “drug” in their lives. Marijuana is a plant that can be cooked and consumed to get this same effect, it’s not a chemical decanted by Merck sold by doctors under the guise of “prescription medicine”. I don’t think there’s reason for negative connotation here. It’s been used as an herbal medicine for literally thousands of years. It’s just since the state was progressively losing money on the liquor tax in the 1930’s due to competition from marijuana that the government/industry push to demonize this plant caused us to think of marijuana as a “drug”.

troubldfinuser2: You might get some good effects in the next few days, or maybe it was too much. Keep us updated! I think I’ve finally found a source so I hope to have some more info soon.

Please make sure that you only try good marijuana, do not consume stick, stems, or seeds. You want buds, mids, or fire. I’m learning the hard way. Consuming the wrong part of the plant can cause problems with anyone.

I had an incredible experience with cannabis recently, it was the nicest high I have ever had in my life with or without the side effects of propecia.

I smoke quite a lot and got very, very high so this sort of counteracts the theory that a little bit is best, so it may be of interest to you guys who aren’t sure whether getting really high will help. Basically I was very jolly, laughing a lot (standard procedure when toking on weed I guess) but then at the end of the night I had sex with my girlfriend and it felt incredible. I had a raging libido, and I felt like I could of ejaculated quite soon like I did before propecia. It was like all my previous senses had been restored 100% and sex once again felt like the best thing ever.

I haven’t seen any improvement since but I thought this was worth posting… I don’t smoke cannabis much, but I definitely feel that occasional use could be a good thing for me now.

i smoke every few days. i hope this isnt hurting my recovery in the long run but prior to taking accutane i smoked every day. while im smoking my penis actually feels kind of number but about an hour and a half into my high i seem to have a decent amount of blood flow. its hard to say how weed effects me because once after work on the way to my girls i smoked a bowl and couldnt get a solid hard on when i got there. i can say for sure that it helps with ejaculation and sensation. normally sex wont feel very good yet for some reason i dont last very long. about an hour after smoking <.5g i can have sex that feels pretty decent and i can last as long as my lady needs. this board is kinda old i just thought id share

I have laid off the weed for a while now, I might try some again soon.

Ive been meaning to post about this for a while. When i smoke weed with my gf my libido shoots up significantly and when we have sex penis sensitivity is amazing.

Got stoned last night and my libido went through the roof. Had that feeling of needing to have sex, telling my gf to hurry up and come to bed. I have not had this feeling post fin.
This is the best treatment plan i have found as funny/wierd as it is.
Pde5i and marijuana :wink:

Note. This is only happening now, probably the tenth time i have been stoned post fin.

if penis sensativty improves (by improve i guess you mean less numbness) then surly this side effect is not a permant one. This is encouraging for me given I have lost 95% of my feeling in that area. Maybe its not nerve damage or cell damage after all.

All other side effects of fin I can live with including ED, but to have a constant numb penis drives me crazzy. i need to get myself some weed.