There has been some conflicting studies on the accuracy of DTC tests, but these are concerns across brands and the tech has improved. Re the privacy stuff, I’m not aware of any issues and I’m personally not concerned regarding the SNPs they have recorded under my name and am more concerned with PFS. Re broader conspiracy stuff…I’ve not heard of a post 23 and me syndrome.
This is simply an extra project those interested can join in on, and requires like-for-like SNP set, so mixing the provider of the tests is not possible. Awor and I believe strongly there is a genetic component to predisposition (imo possibly - based on the data of the ADRs in younger men being more prevalent and severe - in combination with an epigenetic component). This gives us a shot cheaply at correlating a gene involved that, if we were lucky, would be an invaluable find. The “luck” comes down to whether we can find a correlation in the amount of profiles we are able to obtain, and if the gene(s) in question are even checked in the 500,000-620,000 single nucleotide polymorphisms reported by 23andme. They claim to have based their selections on known or suspected associations with health related issues. Bearing in mind there are approximately 20million SNPs in your genome, this project is a dice roll with low odds of an enormous payoff. For me personally, that is worth 60 pounds.