Finasteride induces in male rats long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition

[Mercked]

https://www.sciencedirect.com/science/article/pii/S0306453018305067

pdfft

[axolotl]

Discussion already exists on this study. Have moved posts to existing topic.

Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-reductase enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation and Gut Microbiota Composition (RC Melcangi)

Hello, I’m not sure if this has been posted but Melcangi’s study’s transcript has been released (the one we helped fund). It can be found here: http://sci-hub.tw/https://doi.org/10.1016/j.psyneuen.2018.09.021 I don’t think there’s anything groundbreaking here but perhaps someone who’s more into the science can highlight anything meaningful. On an unrelated note, sage-217 is up on clinicaltrials.gov! They’re aiming to complete Phase 3 by November 2019. Coupled with their priority review statu…