Update:
4 years and 1 months after quitting 1mg/day finasteride for 9 months for male pattern baldness.
Quit finasteride July 2009.
August 2013, just had new blood tests, bio-available T was STILL below acceptable range for a male.
SHBG was also high above range. Estradiol came in at 35 with 39 being the max acceptable range for a male.
Total T was back up in the 500 range… despite the low free/bio-available T … but for me, as my T level has steadily and ever-so-slowly increased after the initial crash 4 years ago, it has not been a good feeling. Day by day the increasing T levels have felt like an increasing auto-immune disease giving me a constant feeling of angst and pains throughout my body and anxiety with occasional panic attacks still occurring despite anxiety meds, and me still feeling trapped in a depressed state despite triple dosages of antidepressants.
I am still battling depression. Have been in and out of it about 4 times the past 4 years - I mean months of severe depression, followed by attempts to pull myself out of it and move ahead and make some medical progress, followed by a relapse to depression as I realize time and time again that part of my anxiety is about something that still remains and hasn’t gone away. This includes painful fibrous scar tissue development on my genitals - which I am going to pursue having removed surgically - and having my testes drop down to what looks more like a 90 year old’s.
The recent blood tests for me were the final straw - given my continuing battle with depression, ADHD, anxiety, memory impairment, trouble concentrating - I decided to move ahead with my transgender hormonal therapy. I had delayed this for a year now to be absolutely cautious and give me time to understand what finasteride syndrome was or still is doing to me. Now I have been on 4mg/day Estradiol and 200mg/day Spironolactone for almost a week.
I notice some changes already - but am going to wait a bit longer before calling it on whether the TG hormonal therapy alleviates any of the anxiety/depression and other symptoms I have felt trapped in after finasteride ravaged my body.
I’m hanging in there and hoping my experience of beginning MTF transgender therapy after being diagnosed with Post Finasteride Syndrome by 4 separate doctors might help shed light on something that could help understand the condition better to help other men who are not transgender.
I’ll keep you posted!
- Mandi McKee