Im not sure if you have read this thread, it is about cyclin D1, which is suppressed by DHT binding to an intact functional AR. It is also suppressed by finasteride.
Here is a quote from an above study
Please keep this thread on topic or it will just end up the same as 99% of the threads on this forum, a general discussion about whatever.
Tim, its really great that there is someone like you willing to keep looking at complex exotic stuff like this, these kind of stuff are most of the time way over our heads including yours, but with a lot of luck it might lead to an interesting path. Im not saying this sarcastically btw, keep doing what youre doing, there is very little chance it might be really relevant, but as little of a chance it may be its worth being taken, you might get lucky and actually hit the jackpot!!
I know you’re not gonna like this, but both tribulus and tamoxifen are potent ANTIFUNGALS (check it on pubmed)
Venceremos, my friend, i am not for or against the yeast argument, the proof is in the pudding.
If you think you have a yeast infection, treat yourself for it and then come back and tell us or brag about how you have recovered.
They may be antifungals but they also decrease cyclin D1, there is an obvious argument for either side.
Interestingly fasting does infact increase nuerogenesis which could explain why fasting seems to improve the mental sides.
[Size=4]Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms.[/size]
Abstract
Although all cells in the body require energy to survive and function properly, excessive calorie intake over long time periods can compromise cell function and promote disorders such as cardiovascular disease, type-2 diabetes and cancers. Accordingly, dietary restriction (DR; either caloric restriction or intermittent fasting, with maintained vitamin and mineral intake) can extend lifespan and can increase disease resistance. Recent studies have shown that DR can have profound effects on brain function and vulnerability to injury and disease. DR can protect neurons against degeneration in animal models of Alzheimer’s, Parkinson’s and Huntington’s diseases and stroke. Moreover, DR can stimulate the production of new neurons from stem cells (neurogenesis) and can enhance synaptic plasticity, which may increase the ability of the brain to resist aging and restore function following injury. Interestingly, increasing the time interval between meals can have beneficial effects on the brain and overall health of mice that are independent of cumulative calorie intake. The beneficial effects of DR, particularly those of intermittent fasting, appear to be the result of a cellular stress response that stimulates the production of proteins that enhance neuronal plasticity and resistance to oxidative and metabolic insults; they include neurotrophic factors such as brain-derived neurotrophic factor (BDNF), protein chaperones such as heat-shock proteins, and mitochondrial uncoupling proteins. Some beneficial effects of DR can be achieved by administering hormones that suppress appetite (leptin and ciliary neurotrophic factor) or by supplementing the diet with 2-deoxy-d-glucose, which may act as a calorie restriction mimetic. The profound influences of the quantity and timing of food intake on neuronal function and vulnerability to disease have revealed novel molecular and cellular mechanisms whereby diet affects the nervous system, and are leading to novel preventative and therapeutic approaches for neurodegenerative disorders.
I dont think I have a yeast infection. I think its an interesting angle because of too many reasons, that we cannot afford to ignore, and I just wanted to share something you might not have known about. Im seem to be pushing it a little strongly only because Im attempting to reestablish some balance on this forum, and Im sure you understand what Im talking about. Now I think your research is interesting too, seriously. Im glad you recognize the obvious arguments for keeping a fungus-related theory in the realm of possibilities.
This being said, I guess I can now tell you that if you beleive in cyclin D1 inhibition as the source of your problems, treat yourself for it and then come back and tell us or brag about how you have recovered? (I hope you understand that your second sentence was uncalled for)