Compounds that potentially reactivate androgen signaling

Went through and put a list of all the compounds that may potentially help us. Maybe these can be incorporated in one of the studies for possible treatments.

HDAC inhibitors:
Depakote/Depakine (Valproic acid)
Parthenolide
Panobinostat
Sulforaphane (Broccoli root extract)

HIV Drugs (very dangerous)
Nevirapine
Efavirenz

Depakote didn’t do anything for me… psych gave it to me for sleep.

How long were you on it for?

whatis the commercial namedrug for sulporaphane?

There is none. Someone should give it a shot, it’s only $3 + shipping and handling: swansonvitamins.com/swanson- … 0-veg-caps

Sodium Butyrate has also been discussed here. I took a bottle of it and while it wasn’t the magic bullet, it was the only thing to help me when my brain fog was at its absolute worst. It also increased memory in mice: en.wikipedia.org/wiki/Histone_de … _neurology

Maybe sulforapane+sodium butyrate might be worth a shot.

Interesting…I was on Depakote for two months (April/May 2012) to help with my sleep, and now that I think about it, it was the last time I had any penile sensitivity. Even though during this period of time my T was around 230 ng/Dl…90 year old man levels - I could feel my penis and had a libido. For the past 8 months I have been on nothing but 15 mg of Remeron for sleep - but I have a libido that is about 1/10 and penile sensitivity that fluctuates from 0/10 to 2/10. I am going to try and get Dr. Goldstein to write me a script for Depakote - I post the results here once I start on it again.

Anyone here take Melatonin for sleep? I was taking a night time herbal capsule with 1mg Melatonin and some other herbs for a month, and have followed up by taking 3mg Melatonin for the last week or so. I am waking up with solid boners every morning with pretty good libido.

*I will mention though throughout my entire PFS I have been able to achieve and maintain about 80-90% erections most of the time, unless the depression hits pretty hard.

What does melatonin have to do with compounds that reactivate androgen signaling? There are numerous threads on melatonin/sleep issues. Use the search function.

if you re gonna use melatonin make sure to use the sub lingual version!! it goes straight into the system

Was just giving my 2 cents about people taking that Depakote stuff for sleep. Just saying that I’ve noticed melatonin is a pretty safe option to try for people with sleep issues.

Did you ever try this again?