Boston's BLOOD RESULTS

Have been following the meso-rx board, and the hypogonadism2 yahoo group for at few years, and have been/are on TRT myself. I always use hcg to not shut down my own testicles. If there is a cure comming, I want to be able to go back to “normal”.

I have tried clomid, TRT with testosterone shots and hcg, and are currently on testogel+hcg, and have seen results with all treatments. The best results have been with testogel and hcg which Im currently on. I have noticed more energy, my libido is better, and Im even starting to have erections at night/morning. My mental function still sucks though, and since thats my main problem, I can’t consider it a success.

Im currently using 5g testogel+100ui hcg and since my testosterone are a little high, I might do hcg 100-150ui every other day instead. Im waiting advise from hypo on that one…

I dont believe in waiting it out, unless you have been off propecia for less than a year.

You don’t look like an ordenary case of propecia-hypogonadism. Your LH (and FSH) looks fine, and your DHT is high. Your SHBG is high (mine is around 20-30) so I think you fall a little out of catagory since most of us are secondary with low LH and low DHT. Even if your FSH was lower this time around, I still look at LH when I compare the bloodresults of us propeciasufferes.

You might be better off than most of us, since your pituitary output seems to be OK. I would go see shippen if I was you.

JH

What are the appointments with Shippen like?
You pay… what is it $550, for like ONE appointment?? And then, what does he then continue treatment over phone and internet, with periodic blood tests?
He seems like a very good, dedicated doctor. I would like to get involved with him, see him, and have him treat me.
So, where do you fly into to see Shippen? What he’s in Penn, right?
So you have to pay for the appointment, and then the plane ticket too…
Again, I know its worth the money to cure from this devastating condition, so I’d pay for it, hands down, it if I had it. Although I don’t really have th money right now, so I may have to plan it out right!

Have you seen him? Does he have you on your current protocol? Does he monitor your treatment on a regular basis, and does it cost you a lot of money? How does that work?

B
thanks for your response too Legend!!

I was wondering about this too. All I have been able to find out is that Dr. Shippen practices in Reading, PA. Boston, I think you might be confusing Dr. Crisler’s fees,etc with Shippen but I’m not sure. I didn’t think Dr. Shippen did over the phone consultations but I’m not sure. I haven’t been able to find any detailed contact information for Dr. Shippen so I hope someone can provide it to us.

my doctor told me today my T went up to !! 671 !! free T 12. I couldn’t believe it!
I followed advice that I got off the internet and didn’t eat for 12 hours prior to testing, I was well rested, also had it taken at 8:21 am.
One other thing, he said he’s still concerned about fertility though because my “FSH is still too high…” @ about 11.5 now, it went up a little again, so he is referring me for a fertility test.
He said my LH is fine. and “cortisol is fine.”

You gave your last free T as 12 in that thread, can I ask what was the given reference range?

And at this time what was your SHBG level…if you do not have one from then what was the last one piror to that test…

Hypo, sorry to not have these earlier. I misplaced these latest test results, some I haven’t even posted yet, but a full panel… I just found them, thankfully!

Taken on 7/10/07 @ 8:50 am

Total T was 652 (ng/dL 280-800)

But Free T 12 (pg/mL 8.8-27.0)

and SHBG 55 H (5-49 NMOL/L)

Prolactin 18 (ng/mL 4-15)
note, it said: “High prolactin *Prolactin elevated, so sample was treated with PEG, which showed more than 60% recovery, suggesting that majority of prolactin is monomeric, and that elevation is not caused by macroprolactin.”

Estradiol 27 (pg/mL 8-45)

and DHT 90 H (25-75 NG/DL)

didn’t get LH or FSH, and I don’t know why because it was requested… Also, there are some other things tested that I just didn’t write here.

Anyway, I hope this can convince SOMEONE I need some treatment, or at least to try some treatment…
What do you think Hypo?? Anyone?
Obviously SHBG is high, but how does Free T look, or Estradiol, and does this high prolactin and DHT tell us anything??

Thanks in advance,
Boston

Obviously free testosterone is near the bottom of the normal range and this is unusual in a young man and something that can account for continued ill health and symptoms of hypogonadism.

I am pretty sure that very few guys on the hypo2 website would think your free testosterone result was good for a guy below 50/60 years of age, but don’t take my word for that. Post your free testosterone result and say little more to influence their thinking and see if they concur with my thoughts……they may go into differing details or request differing information from you, but ultimately I feel they will be of the same mind.

Your Prolactin is just above the upper level of the reference range and your SHBG higher than that typically seen in younger guys. I think your endocrinologist should keep an eye on this level over the next years and if it is increasing an MRI scan should be ordered.

The SHBG is problematic in my view.

It has been mentioned that a one guy didn’t do well on Danazol.

I have been away from the site for some time and so I can’t really jump into details on the individual concerned. What I can say is that Danazol is not a one size fits all treatment. The odds of its success are dependent on a number of factor some of which are unknown. SHBG being a significant factor in the finasteride induced issues is key- as in it being elevated. As we know finasteride can cause problems via multiple mechanisms, no theory involved, this is absolute fact, we see lot of pathology of guys post finasteride with low LH and testosterone and no SHBG issue and we see other guys with high SHBG being part of the problem at hand.

So SHBG needs to be a major factor or the whole issue for Danazol to have a chance of working, there needs to be no other problem that could also be undiagnosed and be independently causing the issues of ill health and even then…we have absolutely no evidence that Danazol works with all men even where elevated SHBG is the main or only issue and no reason to think it will work in all such men.

What we do know is that Danazol is successful in lowering excessive SHBG, that it can increase free testosterone in at least some men as a result and some men have reported success and recovery from finasteride issues as a result.

Like all medications it will have its (as yet unknown) success/failure rate.

What Danazol does offer is the opportunity to lower SHBG and increase free testosterone.

SHBG appear a key issue when it is relatively or overtly high and free testosterone low, particularly if total testosterone is not low or not as low as the free testosterone level.

No other form of TRT to date addresses this issue of SHBG binding of total testosterone that I am aware of.

Thank you very much! I will look into this right away, and keep you updated.

Some latest results of bloods taken two weeks ago:
(Was planning on taking three weeks of Clomid 25mg daily starting today, I just got it yesterday.)

-I guess my Total T is still slowly climbing @ 718 now. Which could be good. Its been 1 year. Last test it was 620 or something.
(can’t remember ranges and dont have it in front of me, but I can update later.)
-I think Free T was somewhere middle range,
-however % T which was also taken, stated BELOW NORMAL RANGE, and was highlighted by the lab.
-FSH was also highlighted by the lab as over and out of the range, OVER NORMAL RANGE.
-LH seemed fine.
-SHGB has come down to 55 I think, middle of range.
Estradiol seems middle of range. Doc said its ok. He thinks I’m getting better.

Am I getting better? I see slow SLOW improvements!??, but nothing to really write home about, because I cant quite tell if its if I’m just managing the problems better, e.g. always trying to wear loose pants, unbuttoning them always when I’m sitting (They’re alwasy falling down when I walk into a store or gas station or something, and I’m like buttoning my pants on the sidewalk! :unamused: ), not drinking nearly as much coffee, staying away from junk food, and most importantly away from stressful situations, or intense situations, and also mostly not drinking ANY ALCOHOL now. It exacerbates everything for a few days.
But still feel the somewhat bloating in my stomach, gassy, crampy stomach most of the time. Something is definately wrong. NEVER used to have this shit, ever in my life.

I think I will be able to get over this, if only… and feel like I am just so SO close, but there’s just gotta be a little something wrong still. Still some prostare symptoms.
Shrinkage is much less frequent. Had some GREAT sex finally though. My woody was pointing straight up :open_mouth: :smiling_imp: when I walked across room to get condom!
But I feel that wouldn’t happen everytime.
Just what is it!!

ps. I defiantely haven’t slept normal since all this started, and I do notice a constant somewhat elevated level of constant stressful state in my body, i.e. like some sort of constant underlying worry, that prevents me from getting to sleep early or sleeping late.
Morning erections about half the time, although short lived, and not as hard as I think they should be accustomed to!
Peace

Any thoughts on hormone levels you experts! :slight_smile:

Need actual test results with ranges to make comments & comparisons, sorry.

This clomid treatment sounds remarkable in its ability to raise testosterone levels. Boston, please let us know how it turns out for you. Has anyone else tried it? Does testosterone remain high even after stopping clomid treatment?

BTW Boston, your Total T is fantastic, why do you want to take Clomid? From what I recall it’s your Free/Bioavailable T that is low, and that can be explained by your elevated SHBG. You also have high Prolactin which would probably be beneficial to bring down.

My guess is without addressing the SHBG or prolactin you likely will see little improvement despite clomid, and may put yourself at risk for unnessecary side effects (visual tracers), not to mention messing with your hormones again by causing a hormone surge.

You also have elevated FSH, have you had sperm test done to check your fertility?? Usually elevated FSH is linked to Primary Testicular failure but in your case you obviously are pumping out a lot of T so that is unlikely.

labtestsonline.org/understan … /test.html

"In men, high FSH levels are due to primary testicular failure. This can be due to developmental defects in testicular growth or to testicular injury, as indicated below.

Developmental defects:

-Gonadal agenesis
-Chromosomal abnormality, such as Klinefelters syndrome

Testicular failure:

-Viral infection (mumps)
-Trauma
-Radiation
-Chemotherapy
-Autoimmune disease
-Germ cell tumor "

So if you are producing tons of T yet have elevated FSH, that leaves “INHIBIN B” since it also regulates FSH:

humrep.oxfordjournals.org/cgi/co … l/14/4/906

“In conclusion, the results of this study demonstrate that: (i) in humans, the production of inhibin B by Sertoli cells reflects interactions between these cells and spermatids; (ii) in oligozoospermic subjects, low plasma concentrations of inhibin B as well as high plasma FSH concentration identify pathological conditions characterized by a severe depopulation of seminiferous tubules; (iii) elevated plasma FSH concentrations are not always indicative of a decrease of inhibin B production, and in this case a normal inhibin B concentration demonstrates the presence of a residual function of tubular cells related to the presence of spermatids”

jcem.endojournals.org/cgi/conten … 86/11/5541

"There is now an abundance of literature attesting to the importance of Inh B as an important endocrine feedback regulator of FSH secretion in the human male "

hey boston,

you are a prime candidate for PCT b/c your FSH and LH are high, but you still have low total testosterone. LH fluctuates during the day and it is hard to determine if you have low LH, but with 4.3 seems to be pretty normal. I think if you took hcg to start up your testes then your total testosterone will increase along with the free testosterone.

this is a snipet of Boston’s Lab work
fsh 10 (2-12)
lh 4.3 (2-10)
free testos 6 (8.8-27)
total testos 379 (280-800)
Estradiol 18 (8-45)

Today, I’m going get my lab results (prior to PCT) then i’ll check to see if I can get tested within the next couple of days to see if PCT has increased testosterone.

Thats cool. Just make sure you get them done from the same lab, at same time of day obviously, but also try to replicate diet and daily schedule and activity surrounding your testings…
I would really like to hear what your findings are.
Peace man, thanks!

I wonder if I do end up signing up with Crisler this month, if he will go ahead with similar… I am curious, because I like what you have to say. Later…

Boston,

Why are you signing up with Crisler? I thought you had gotten over all of this crap already.

Not quite bro! Almost, but not quite. Still have always wanted to go on some PCT. Would love to have those explosive erections and libido again, you know like when you just start thinking about a girl you have a chance with. I’m almost there. Its all in the PROCESS man! This is going to be part of my process, because I can, and am not afraid either.

What is it that you hope or expect him to put you on?

whassup boston,

yea i got my labs and posted the results on my PCT journal. it seems that my testosterone has increased dramatically prior to PCT. I think it is the combination of royal jelly and better sleep.

if you see chrisler, then i hope you it works out for you. You should read stuff on meso-rx.com where steroid users try to restore hpta. anyhow, stay tuned with my PCT journal b/c i put almost every result there. I try to have a one stop shop approach to detailing my experience. there are member stories and blood and hormone results that i still have to post. Just too many threads to keep track of.

definitely keep this brutha informed! oneday

I have read all around on MesoRX forum, many times, for hours and hours. There is so much stuff on there!! I don’t know where to follow, or what to look for, so this is why I’m hoping to have a doctor beside me, helping to guide me, while also providing referals for blood testing and regular lab-work.

Isn’t Dr. Crisler supposed to be one of the very best in this situation? I would thing he would prescribe me a similar stack maybe… no!? I’ll certainly ask him, and recommend it, based on what you have explained about it.

Who knows, maybe I’ll hopefully going to you fo treatment for recovery soon :smiley:

Thanks man!

B