Ok so I’ve been thinking now we’re getting to a point where we have a few theories as to the problem we experience. So I thought I would put a list of tests that we should have done in lab setting:
Ones we can’t easily do without:
Adiol 17-G
Adiol 3-G
11b-OH-Etiocholanolone
androsterone/etiocholanolone
11ß-hydroxy androsterone/11ß-hydroxy etiocholanolone
5-tetrahydrocorticosterone (THB)/THB
5-THF/THF
Genital Skin Fibroblast testing
Genetic test for AR gene mutation
Genetic test for 5AR2 mutation
6b-hydroxy-5a-dihydrotestosterone
6beta-hydroxy testosterone
7α-hydroxytestosterone
Ratio of hydroxy-testosterone to normal testosterone
4-androstene,16,17β-diol-3-one (16-OH-testosterone)
AR gene CAG and GGC repeats
Determine if 17B-hydroxysteroid dehydrogenase pathway is working - testosterone to Δ4-androstenedione ratio
Determine if 3 beta-hydroxysteroid dehydrogenase deficiency
Genome wide methylation analysis - concentrating on AR receptor function and CYP… enzymes in liver. - see studies in viewtopic.php?f=5&t=3901&start=120 for which areas.
The usual:
Total testosterone
Bioavailable Testosterone
Free Testosterone
DHT
FSH
LH
SHBG
Free t3
Free t4
TSH
DHEAs
Androstendione
Estradiol
24 hour cortisol
Progesterone
Prolactin
Vitamin D
Zinc
IGF-1
IGF-BP3
CRP
ESR
This should cover everything. Any other suggestions?