Suspect you have read this one before. It also shows a decrease in transcription of 5-ar type I and a 3a-HSD enzyme (DHRS9)
A. M. Nelson, W. Zhao, K. L. Gilliland, A. L. Zaenglein, W. Liu, and D. M. Thiboutot, “Temporal changes in gene expression in the skin of patients treated with isotretinoin provide insight into its mechanism of action,” Dermato-Endocrinology , vol. 1, no. 3, pp. 177–187, May 2009.
Full PDF link:
http://www.tandfonline.com/doi/pdf/10.4161/derm.1.3.8258?needAccess=true
…A 6-fold decrease in HSD3B1
I’m not sure. Retinoic acid stimulated neurosteroidogenesis in glial cells and induction of HSD3B was noted, along with p450scc and StAR: