Welcome to our community. Please fill in the following template as a way of introducing yourself, and helping others to understand your background and situation.
Where are you from (country)? Finland
How did you find this forum (Google search – if so, what search terms? Via link from a forum or website – if so, what page? Other?) people
What is your current age, height, weight? 51, 175,75
What specific drug did you use (finasteride, dutasteride, saw palmetto, isotretinoin/Accutane, fluoxetine, sertraline, citalopram, leuprorelin, etc…)?
agomelatine 3 months 25mg adding bupropion 150mg for 5 days then 300mg for 10 days and total destruction
What dose did you take (eg. 1 mg/day, 1 mg every other day etc.)?
What condition was being treated with the drug?
depression of life crisis. In reality I was anxious but could not describe it more than being depressed. All new to me.
For how long did you take the drug (weeks/months/years)?
How old were you, and WHEN (date) did you start the drug?
How old were you when you quit, and WHEN (date) did you quit?
2017 48 yo
How did you quit (cold turkey or taper off)?
How long into your usage did you notice the onset of side effects?
I noticed some numbing and anhedonia from the agomelatine alteady plus significant anxiety increase. Quite soon after start. Adding the bupropion exploded my anxiety.
What side effects did you experience that have yet to resolve since discontinuation?
loss of all sexual stimuli and function
total loss of reward / motivation
numb genitals and other areas
occasional severe anxiety attacks
total loss of everything in life
Check the boxes that apply. You can save your post first, then interactively check/uncheck the boxes by clicking on them. If your symptoms change, please update your list.
[ x] Loss of Libido / Sex Drive
[ x] Erectile Dysfunction
[ x] Loss of Morning Erections
[ x] Loss of Spontaneous Erections
Loss of Nocturnal Erections
[ x] Watery Ejaculate
[ x] Inability or Difficulty to Ejaculate / Orgasm
Reduced Sperm Count / Motility
[ x] Emotional Blunting / Emotionally Flat
[ x] Difficulty Focusing / Concentrating
[ x] Memory Loss / Forgetfulness
Stumbling over Words / Losing Train of Thought
Slurring of Speech
[ x] Lack of Motivation / Feeling Passive / Complacency
[ x] Extreme Anxiety / Panic Attacks
[ x] Severe Depression / Melancholy
Penile Tissue Changes (narrowing, shrinkage, wrinkled)
Penis curvature / rotation on axis
[ x] Testicular Pain
Testicular Shrinkage / Loss of Fullness
[ x] Genital numbness / sensitivity decrease
Gynecomastia (male breasts)
[ x] Muscle Wastage
[ x] Muscle Weakness
Dry / Dark Circles under eyes
[ x] Persistent Fatigue / Exhaustion
Stomach Pains / Digestion Problems
[ x] Constipation / “Poo Pellets”
Vision - Acuity Decrease / Blurriness
[ x] Tinnitus (ringing or high pitched sound in ears)
Increased hair loss
Lowered body temperature
[ x] Other (please explain)
rest pulse 110
What (if any) treatments have you undertaken to recover from your side effects since discontinuation of the drug?
was given further drugs at hospital against my will 5 weeks (seroquel, cipralex). Was taken to hospital because the initial crash simply paralysed me.
If you have pre or post-drug blood tests, what hormonal changes have you encountered since discontinuing the drug (please post your test results in the “Blood Tests” section and link to them in your post)?
Anything not listed in the above questions you’d like to share about your experience?
insomnia and loss of appetite from the drugs in hospital. Not cured.
Tell us your story, in your own words, about your usage and side effects experienced while on/off the drug.
have tried various drugs for sleep only xanax helps a bit
sleep not restful/deep
also tried moclobemide and low dose pramipexole for anhedonia no help. Tried ketamine Iv once, no help.
Alcohol has no effect, nicotine no, coffee no
all in all seems like a catastrophical dopanine/androgen system damage with bodily numbness