Took F for 17 yrs


Fair enough but there are 5,000 forum members and gazillions of posts. I can’t possibly weed through these. Surely, a veteran forum member can report “there have been very few/some/lots of PFS victims/forum members who have reported recovering full potency.”

From what I’ve seen so far, it’s extraordinarily rare for PFS victims - especially those who got “full blown” PFS (black eyes, breasts, penis pain, insomnia, etc.) - to ever recover full potency like me.

And the only “special/unusual” thing I tried was 5 days of steroids (methylprednisolone) injection into the bloodstream, which MAYBE the “miracle” cure we’ve all been trying to find.



Bro your grandfather didn’t look like he lost that much hair. I can’t see the crown so he might be bald there but if all he lost was frontal he could’ve easily gotten a pretty good transplant and maybe you could’ve too. Too late now though.

Well you kind of didn’t become fully potent again if you don’t have spontaneous sexual thoughts or erections. That’s a big difference, I have night and morning wood but I don’t get spontaneous thoughts during the day at all. You’re supposed to get them so your dick stays straight lol. Methylprednisolone could’ve helped you, anything’s possible. Post it in the Drug forum maybe some other people would like to try it.

This forum isn’t anywhere near conclusive on people who’ve gotten better or not. A lot of people don’t even know about it. I’ve come across random reddit threads about people getting better randomly after months or years so people do heal, but again there’s no way to get an accurate figure.

I see Erwig’s point if even he was just saying it casually. If you’ve taken it for over a decade what’s a few more pills gonna hurt lol, but it’s your body, your decision so I get why you don’t want to do it either.


Well on a positive note, I’m donating blood Saturday for the first time in 20 years!

'Tis the season :wink:


Dude u crazy for taking Finasteride for that…Not pattern balding Everyones hair changes from teen age years even those that maintain all of their hair and don’t bald…Hair changes naturally as you age…Nothing u can do about that it’s called mature hair line…And any Dr that would suggest you get back on fin I would question his sanity and whether he should maintain a license to practice…Hard to believe the men that have fucked themselves up with this brain damaging drug who didn’t even have hair loss…


What symptoms were you being treated for that they gave you methyl? Why did they think you may have an autoimmune disorder? Were they familiar with PFS and did you present yourself as a PFS sufferer?


The Mayo Clinic neuro hoped to improve my walking ability/body coordination, which is severely impaired. The methyl did not help that but POSSIBLY helped my ED. The sexual plumbing has worked perfectly for 4.5 months, after being dead as a doornail for 2.5 years.

Like ALL the docs I’ve dealt with, they blew off my thoughts about PFS.


are you saying that you have regained full potency from 4.5 month ago and it is still working, Man that is a good news congratz and hopefully all of your other symptoms will get better too. Enjoy.
one thing you think that methyl P, cured you from impotence ??


Yep potency 100% restored, PERHAPS due to methyl, or luck, or healing over time.


Aloha, my neurologist suggested I write a DETAILED chronology to assist him, so I’m updating my old profile. According to him, I am a medical “zebra” case - extremely unusual in many respects so it is worth reading.


In summary, I’m a 50yo retired-for-now lawyer. I religiously took 1mg FIN daily from 1999-2014. I started losing the ability to sleep in June 2014 and had no clue it was related to FIN. By Dec I had stopped sleeping ENTIRELY and discontinued FIN. 10 days later post-finasteride exploded my brain!

The fantastic news is that I VERY FORTUNATELY recovered 100% from total loss of libido (after 2 years), total physical impotence (2.5 years), frightening delusions (2 months), total loss of emotionality/compassion/feelings (6 months), breast development (2 months), intense penis pain (1 month), and - oddly - my facial hair 100% stopped growing for 4 months and then resumed normal growth!

The bad news is my sleep remains profoundly dysfunctional. I very rarely reach unconsciousness and just “heavy rest” 4 hours at night - with Balsomra sleeping pill - and take “heavy rest” naps 1-2 times randomly.

See this article:








OR TRY BOTH remeron/nortryptilin, which 100% solved my sleep dysfunction from April 2015-Dec. 2016; and inexplicably STOPPED working.


so you think its not curable in the next 1000 years ? sounds optimistic…


and do you mean with skipping doses in 2014 taking it every other day ? or really skipped it a few days in usage ?


To Mohi Khera, Baylor University

Hello Dr, Thank you for your response

I just want to pass you an information that could also help you out to find answers and even a possible treatment

The following study and research indicated that SRD5A2 is silenced in prostate tissue.


Variable expression of 5-alpha reductase 2 in the aging adult prostate is regulated by DNA methylation


5-alpha reductase type 2 (SRD5A2), an enzyme that is critical for prostatic development and growth, is utilized as an inhibitory target by finasteride for patients with bladder outlet obstrution secondary to BPH. However, we have found that many aging benign prostate tissues do not express the enzyme. Since the SRD5A2 promoter contains a CpG island, we hypothesized that somatic methylation of the promoter would be regulated by DNA methyltransferases leading to suppression of SRD5A2.


We found that methylation of SRD5A2 was regulated by DNA methytransferase 1 (DNMT1) and the cytokines, TNF-alpha, NF-κB and IL-6, regulated DNMT1protein expression and thereby indirectly affected SRD5A2 promoter methylation and gene expression.

Induction of inflammation with lipopolysaccharide (LPS) stimulated the TNFR1/NF-κB/IL-6/DNMT1 pathway, leading to hypermethylation of the SRD5A2 promoter and silencing of SRD5A2, while treatment with both LPS and TNF-alpha inhibitor reversed this pathway and reactivated SRD5A2.

From Propecia Help Forum

I found a guy that his symptoms were reversed, by accident when his doctor administered intravenous 1000 mg of methylprednisolone for 5 days, 5 months later his sexual functions including libido was 100% restored and all the others symptoms disappear.

only his sleep remain dysfunctional.

For those who doesn’t know methylprednisolone is a LPS and TNF-alpha inhibitor, is an immune suppressant.

I hope that every one got the idea.

Gentlemen believe or not, we are in from of a possible miracle cure if methylprednisolone is used within the proper protocol and the right dosage.


Had anyone else tried methylprednisolone with any success?


Scott. H until now I guess that Nobody, especially at the dosage that anonymous did, the only problem here is to find a doctor willing to give us methylprednisolone and @1000mg for five days