Androgen receptor overexpression and sensitivity to hormones reversed by epigenetic therapy that restores Pur-α to a transcriptional repressor complex of AR deregulated in HRPC

Why not try it yourself along with Keto diet? @Mercked

Did you?

Yes, except BHB. I can’t order it. They don’t ship here. I would if i could. It is safe and healthy.

1 Like

That’s the thing. There are zero studies on R-BHB. Just an example.

Honestly Merck give intermittent fasting/low carb a go I’ve been doing it for 2 days and have felt better, I’ve been in this crap for nearly 3 years now. I haven’t tried bhb yet but have been eating butter/cheese.

1 Like

Sorry, I meant L-BHB, which is keto salts. There are literally no human studies on it whatsoever. It’s an untested artificially manufactured substance.

D-BHB is what our bodies make and that has been tested in supplement form. Only two companies make it, however both contain stevia as a sweetener which is a progesterone receptor antagonist. Stevia also inhibits the growth of l. Reuteri in the gut.

1 Like

Why not just do fasting and keto diet? That should increase the amount of hydroxybutyrate needed for demethylation.

I do IF given how much time i spend trying to go back to sleep. Not going to step on the hornets nest wrt keto but imo it’s not something Id even want to consider doing and I’ll leave it at that.

@joshuk vorinostat - can you remember what daily dose you took and how long you took it for - thanks

Try HMB. There’s a brand called Clear muscle. It converts into hydroxybutyrate and it has been tested in humans. I’ve been using it to prevent muscle wasting but it seems like it could be good for demethylation too.

Thanks! I’ll definitely look into it.

no idea on doseage it was all on solvepfs but its gone now . their was a specific dosage to take though as it did something with blood . IMMO on solve pfs took it as well but he is no longer with us sadly.

i think we could only take it for less than 2 weeks due too cleaving cells but we had no results either way you can buy the powder from china we got it tested it was legit

Hello Mercked, I leave this exactly message in other posted subject:

This message are for those with the spirit to fight to get well.

I am here back to report that I am doing really well, no problem at all, really good overall health, my sexual health is amazing again, really good erection, really good libido, enjoying porn like never before, good mod, good mental health, zero stress anxiety and zero depression. extremely stable, not setback I came to the conclusion that I am recovered 100%. (Still waking up in the middle of the night but able to go back to sleep " But it is probably normal " ).

This is my opinion:

Guys this is reversible IF you take on own hand your own situation and FIGHT for it, NOW IF you are going to be seating doing absolutely nothing ( a seating duck waiting for a research that probably find something in 10 years and another 10 years to come to the conclusion to that maybe they have a treatment or maybe that they didn’t find anything conclusive) it is up to you guys.

Every thing that I did is posted in this forum nothing new

The only thing that I recommend to everyone is walk for 35 to 45 minutes without stop everyday if possible, it is really good for the brain.

Note: Everything that is good for the BRAIN is good to fight PFS…

Food that support gut health is good for the brain…
Aerobic exercise is good for the brain…
Zero stress is good for the brain and the list goes on…


Thanks. Would you attribute your recovery in part to taking BHB salts?

1 Like

It is possible, and also butyrate.
This is my recommendation:

1-I recommend 35 to 45 minutes walk every day.
Healthy diet, avoid stress ( All this is good for the brain ).
2-( Butyrate and BHB, vitamin C ) all together.
3-Decaffeinated Coffee
4-Ginger powder
Fish oild is good for the brain also.

Good luck to all.


My tendons are broken, my muscles disappeared, every part of my body hurt, i can’t coordinate my inches. If I walk for 100 steps, I need to call an ambulance. How can I walk for 30-35 minutes every day?

1 Like

Wow man you are in the worse PFS case that I ever heard of.
I am sorry.

Serotonin was my first poison, it fucked up my dick. After some month, zinc and Tribulus totally fucked up my body.

Thanks MOON! I’m really stoked you’re 100% now, excellent news. :slight_smile:

Could you remind us of your exact daily dosages for Butyrate, BHB and vitamin C?

Thanks again buddy. :slight_smile: